Cell therapy using allogeneic bone marrow mesenchymal stem cells prevents tissue damage in collagen‐induced arthritis
A Augello, R Tasso, SM Negrini… - Arthritis & …, 2007 - Wiley Online Library
Abstract Objective Mesenchymal stem cells (MSCs) are precursors of tissue of mesenchymal
origin, but they also have the capacity to regulate the immune response by suppressing T …
origin, but they also have the capacity to regulate the immune response by suppressing T …
Reversal of the immunosuppressive properties of mesenchymal stem cells by tumor necrosis factor α in collagen‐induced arthritis
F Djouad, V Fritz, F Apparailly… - Arthritis & …, 2005 - Wiley Online Library
Objective Adult mesenchymal stem cells (MSCs) represent promising tools for therapeutic
applications such as tissue engineering and cellular therapy. Recent data suggest that, due …
applications such as tissue engineering and cellular therapy. Recent data suggest that, due …
Mesenchymal stem cells are conditionally therapeutic in preclinical models of rheumatoid arthritis
A Papadopoulou, M Yiangou, E Athanasiou… - Annals of the …, 2012 - ard.bmj.com
Objective The role of mesenchymal stem cells (MSC) in experimental arthritis is undoubtedly
conflicting. This study explored the effect of bone marrow-derived MSC in previously …
conflicting. This study explored the effect of bone marrow-derived MSC in previously …
Immunosuppressive effects of mesenchymal stem cells in collagen-induced mouse arthritis
F Mao, WR Xu, H Qian, W Zhu, YM Yan, QX Shao… - Inflammation …, 2010 - Springer
Objective The objective of this study was to investigate the efficacy of mesenchymal stem
cell (MSC) in the treatment of arthritis. Methods Mesenchymal stem cells were injected …
cell (MSC) in the treatment of arthritis. Methods Mesenchymal stem cells were injected …
Transforming growth factor β–transduced mesenchymal stem cells ameliorate experimental autoimmune arthritis through reciprocal regulation of Treg/Th17 cells and …
MJ Park, HS Park, ML Cho, HJ Oh, YG Cho… - Arthritis & …, 2011 - Wiley Online Library
Objective Bone marrow–derived mesenchymal stem cells (MSCs) can prevent various
autoimmune diseases. We examined the therapeutic potential of transforming growth factor …
autoimmune diseases. We examined the therapeutic potential of transforming growth factor …
[HTML][HTML] Mesenchymal stem cell-conditioned medium reduces disease severity and immune responses in inflammatory arthritis
AG Kay, G Long, G Tyler, A Stefan, SJ Broadfoot… - Scientific reports, 2017 - nature.com
We evaluated the therapeutic potential of mesenchymal stem cell-conditioned medium (CM-
MSC) as an alternative to cell therapy in an antigen-induced model of arthritis (AIA). Disease …
MSC) as an alternative to cell therapy in an antigen-induced model of arthritis (AIA). Disease …
[HTML][HTML] Intra-articular injection of mesenchymal stem cells leads to reduced inflammation and cartilage damage in murine antigen-induced arthritis
Background Rheumatoid arthritis (RA) is a debilitating and painful disease leading to
increased morbidity and mortality and novel therapeutic approaches are needed. The …
increased morbidity and mortality and novel therapeutic approaches are needed. The …
[HTML][HTML] Discrepancy between the in vitro and in vivoeffects of murine mesenchymal stem cells on T-cell proliferation and collagen-induced arthritis
E Schurgers, H Kelchtermans, T Mitera… - Arthritis research & …, 2010 - Springer
Introduction The goal of this study is to analyze the potential immunosuppressive properties
of mesenchymal stem cells (MSC) on T cell proliferation and in collagen-induced arthritis …
of mesenchymal stem cells (MSC) on T cell proliferation and in collagen-induced arthritis …
Mesenchymal stem cells, autoimmunity and rheumatoid arthritis
The vast majority of literature pertaining to mesenchymal stem cells (MSC)
immunomodulation has focussed on bone marrow-derived MSC that are systemically …
immunomodulation has focussed on bone marrow-derived MSC that are systemically …
[HTML][HTML] Mesenchymal stem cell-based therapy for rheumatoid arthritis
M Sarsenova, A Issabekova, S Abisheva… - International journal of …, 2021 - mdpi.com
Mesenchymal stem cells (MSCs) have great potential to differentiate into various types of
cells, including but not limited to, adipocytes, chondrocytes and osteoblasts. In addition to …
cells, including but not limited to, adipocytes, chondrocytes and osteoblasts. In addition to …
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