This study tested the hypothesis that an A1 adenosine receptor capable of inhibiting
adenylate cyclase activity is present in porcine coronary vascular smooth muscle cells. In the …

Myocardial metabolites such as adenosine mediate reactive hyperemia, in part, by activating
ATP-dependent K+ (KATP) channels in coronary smooth muscle. In this study, we …

To clarify the relative roles of A2 adenosine receptor subtypes in the regulation of coronary
flow and myocardial contractility, coronary vascular and functional responses to adenosine …

It has been postulated that the adenosine A1receptor subtype, but also A2Areceptors, are
involved in mediating the beneficial properties of adenosine during ischemia and …

1 The effects of myocardial ischaemia/reperfusion were tested on the coronary vasorelaxant
responses to agonists selective for the A1 and A2 adenosine receptor subtypes in the dog …

Microvascular exchange is essential for maintaining body fluid and functional homeostasis.
Adenosine (ADO), a metabolite of nucleotide, plays important roles in cardiovascular …

Adenosine increases coronary flow mainly through the activation of A 2A and A 2B
adenosine receptors (ARs). However, the mechanisms for the regulation of coronary flow …

Adenosine is a potent vasodilator that plays an important role in the regulation of coronary
microvascular diameter. Although multiple adenosine receptor subtypes have been recently …

In this study, we looked into possible compensatory changes of other adenosine receptors
(ARs) in A2A genetic knockout mice (A2AKO) as well as the functional role of nitric oxide …

In this study, we have investigated the mechanism of ADP‐induced relaxation of porcine
coronary artery (PCA) rings. The P2Y receptor agonists ADP and ADPβS produced …