The scent of colorectal cancer: detection by volatile organic compound analysis

NKH de Boer, TGJ de Meij, FA Oort, IB Larbi… - Clinical …, 2014 - Elsevier
The overall metabolic state of an individual is reflected by emitted volatile organic
compounds (VOCs), which are gaseous carbon-based chemicals. In this review, we will …

Electronic nose can discriminate colorectal carcinoma and advanced adenomas by fecal volatile biomarker analysis: proof of principle study

TG de Meij, IB Larbi, MP van der Schee… - … journal of cancer, 2014 - Wiley Online Library
In the course and prognosis of colorectal cancer (CRC), early detection and treatment are
essential factors. Fecal immunochemical tests (FITs) are currently the most commonly used …

Application of fecal volatile organic compound analysis in clinical practice: Current state and future perspectives

S El Manouni el Hassani, DJC Berkhout, S Bosch… - Chemosensors, 2018 - mdpi.com
Increasing interest is noticed in the potential of volatile organic compound (VOC) analysis as
non-invasive diagnostic biomarker in clinical medical practice. The spectrum of VOCs …

Volatile organic compounds as new biomarkers for colorectal cancer: a review

M Di Lena, F Porcelli, DF Altomare - Colorectal Disease, 2016 - Wiley Online Library
Abstract Analysis of the volatile part of the metabolome (volatile organic compounds, VOC)
present in the gas phase of excreted materials is a promising new screening tool for several …

Are volatile organic compounds accurate markers in the assessment of colorectal cancer and inflammatory bowel diseases? A review

F Vernia, M Valvano, S Fabiani, G Stefanelli, S Longo… - Cancers, 2021 - mdpi.com
Simple Summary Early diagnosis is crucial for reducing colorectal cancer-related mortality in
both the general population and inflammatory bowel disease. Volatile organic compound …

Volatile organic compounds emitted from faeces as a biomarker for colorectal cancer

A Bond, R Greenwood, S Lewis, B Corfe… - Alimentary …, 2019 - Wiley Online Library
Background Colorectal cancer remains a leading cause of mortality and morbidity. The UK
Bowel Cancer Screening Programme (BCSP) has demonstrated that detection of colorectal …

[PDF][PDF] Volatile organic compounds (VOCs) found in urine and stool

B de Lacy Costello, NM Ratcliffe, A Amann… - … non-invasive diagnosis …, 2013 - academia.edu
VOC analysis of small molecules is a facile method for assessing stool and urine. Gut
chemistry is exceedingly complex and the results of VOC analysis offer a simplified picture of …

Colorectal cancer screening with odour material by canine scent detection

H Sonoda, S Kohnoe, T Yamazato, Y Satoh… - Gut, 2011 - gut.bmj.com
Objective Early detection and early treatment are of vital importance to the successful
treatment of various cancers. The development of a novel screening method that is as …

Identification of Volatile Markers of Colorectal Cancer from Tumor Tissues Using Volatilomic Approach

L Mezmale, M Leja, AM Lescinska, A Pčolkins… - Molecules, 2023 - mdpi.com
The human body releases numerous volatile organic compounds (VOCs) through tissues
and various body fluids, including breath. These compounds form a specific chemical profile …

Digging deeper into volatile organic compounds associated with cancer

S Janfaza, B Khorsand, M Nikkhah… - Biology Methods and …, 2019 - academic.oup.com
Volatile organic compounds (VOCs), produced and emitted through the metabolism of
cancer cells or the body's immune system, are considered novel cancer biomarkers for …