[HTML][HTML] Butyrate ameliorates inflammation of alcoholic liver disease by suppressing the LPS-TLR4-NF-κB/NLRP3 axis via binding GPR43-β-arrestin2

Y Ren, R Wang, J Yu, T Bao, Y Liu, Z Bai… - Journal of Functional …, 2022 - Elsevier
Alcoholic liver disease (ALD) regarding to liver damage caused by alcohol abuse is
characterized by chronic liver inflammation, with dysregulations of the gut microbiota and its …

CBD alleviates liver injuries in alcoholics with high-fat high-cholesterol diet through regulating NLRP3 inflammasome–pyroptosis pathway

X Jiang, Y Gu, Y Huang, Y Zhou, N Pang… - Frontiers in …, 2021 - frontiersin.org
Alcohol abuse and high-fat diet–induced liver diseases have been the most prevalent
chronic liver diseases and the leading reasons for liver transplantation around the world …

Lemon balm and dandelion leaf extract synergistically alleviate ethanol‐induced hepatotoxicity by enhancing antioxidant and anti‐inflammatory activity

BR Choi, IJ Cho, SJ Jung, JK Kim… - Journal of Food …, 2020 - Wiley Online Library
We investigated the effect of a 2: 1 (w/w) mixture of lemon balm and dandelion extracts (LD)
on ethanol (EtOH)‐mediated liver injury and explored the underlying mechanisms …

Auranofin attenuates non-alcoholic fatty liver disease by suppressing lipid accumulation and NLRP3 inflammasome-mediated hepatic inflammation in vivo and in vitro

H Hwangbo, MY Kim, SY Ji, SY Kim, H Lee, GY Kim… - Antioxidants, 2020 - mdpi.com
Non-alcoholic fatty liver disease (NAFLD) causes liver dysfunction and is associated with
obesity and type 2 diabetes. Chronic inflammation is associated not only with the …

Patchouli alcohol ameliorates acute liver injury via inhibiting oxidative stress and gut-origin LPS leakage in rats

L Xu, Q Huang, X Tan, Q Zhao, J Wu, H Liao… - International …, 2021 - Elsevier
Alcoholism represents a predisposing factor for liver-related morbidity and mortality
worldwide. Pogostemon cablin has been widely used in China for the treatment of digestive …

Chlorogenic acid ameliorated non-alcoholic steatohepatitis via alleviating hepatic inflammation initiated by LPS/TLR4/MyD88 signaling pathway

X Gu, M Wei, F Hu, H Ouyang, Z Huang, B Lu… - Chemico-Biological …, 2023 - Elsevier
Non-alcoholic steatohepatitis (NASH) is a severe pathological stage in non-alcoholic fatty
liver disease (NAFLD) and is generally recognized to be induced by chronic inflammation …

Pterostilbene Protects Against Lipopolysaccharide/D-Galactosamine-Induced Acute Liver Failure by Upregulating the Nrf2 Pathway and Inhibiting NF-κB, MAPK, and …

E Zhang, J Huang, K Wang, Q Yu, C Zhu… - Journal of Medicinal …, 2020 - liebertpub.com
The purpose of this study was to evaluate the protective effect of pterostilbene (Psb) against
lipopolysaccharide and D-galactosamine (L/D)-induced acute liver failure (ALF) in mice and …

Maltol improves APAP-induced hepatotoxicity by inhibiting oxidative stress and inflammation response via NF-κB and PI3K/Akt signal pathways

Z Wang, W Hao, J Hu, X Mi, Y Han, S Ren, S Jiang… - Antioxidants, 2019 - mdpi.com
Maltol, a food-flavoring agent and Maillard reaction product formed during the processing of
red ginseng (Panax ginseng, CA Meyer), has been confirmed to exert a hepatoprotective …

Glycycoumarin ameliorates alcohol-induced hepatotoxicity via activation of Nrf2 and autophagy

X Song, S Yin, Y Huo, M Liang, L Fan, M Ye… - Free Radical Biology and …, 2015 - Elsevier
Licorice, a traditional Chinese medicine, has been used to treat various diseases, including
liver disease, for centuries. However, the chemical basis and biological mechanisms …

Simultaneous modulation of NLRP3 inflammasome and Nrf2/ARE pathway rescues thioacetamide-induced hepatic damage in mice: role of oxidative stress and …

DK Dwivedi, GB Jena - Inflammation, 2022 - Springer
Chronic tissue injury resulting in fibrosis of multiple organs, responsible for one-third of the
death globally. Liver fibrosis is a common pathway/condition involved in all chronic liver …