[HTML][HTML] Protective effects of ellagic acid against alcoholic liver disease in mice

L Zhao, A Mehmood, MM Soliman, A Iftikhar… - Frontiers in …, 2021 - frontiersin.org
Ellagic acid, a natural polyphenolic compound commonly present in vegetables, fruits, nuts,
and other edible plants, exerts many pharmacological activities. The present project was …

[HTML][HTML] Artemisitene alters LPS-induced oxidative stress, inflammation and ferroptosis in liver through Nrf2/HO-1 and NF-kB pathway

C Zhao, C Xiao, S Feng, J Bai - Frontiers in pharmacology, 2023 - frontiersin.org
The liver plays a critical role in sepsis, which is a serious worldwide public health problem. A
novel mechanism of controlled cell death called ferroptosis has recently been described …

[HTML][HTML] Regulation of NOX/p38 MAPK/PPARα pathways and miR-155 expression by boswellic acids reduces hepatic injury in experimentally-induced alcoholic liver …

RM Salama, SS Abbas, SF Darwish, AA Sallam… - Archives of pharmacal …, 2023 - Springer
Alcoholic liver disease (ALD) refers to hepatic ailments induced by excessive alcohol intake.
The pathogenesis of ALD comprises a complex interplay between various mechanistic …

Resveratrol modulates autophagy and NF-κB activity in a murine model for treating non-alcoholic fatty liver disease

L Li, J Hai, Z Li, Y Zhang, H Peng, K Li… - Food and Chemical …, 2014 - Elsevier
In this study, we aimed to investigate the therapeutic effects and involved mechanisms of
resveratrol on an established non-alcoholic fatty liver disease (NAFLD) murine model. Wild …

Echinacoside from Cistanche tubulosa ameliorates alcohol‐induced liver injury and oxidative stress by targeting Nrf2

Y Ding, Y Zhang, Z Wang, F Zeng, Q Zhen… - The FASEB …, 2023 - Wiley Online Library
Abstract Cistanche tubulosa (Schrenk) Wight, named Guan hua Rou Cong‐Rong in
Chinese, is a traditional plant with liver, kidney, and intestine protective effects …

Astragaloside IV ameliorate acute alcohol-induced liver injury in mice via modulating gut microbiota and regulating NLRP3/caspase-1 signaling pathway

S Wu, F Wen, X Zhong, W Du, M Chen… - Annals of Medicine, 2023 - Taylor & Francis
Abstract Purpose Astragaloside IV (AS-IV) is a natural saponin substance extracted from the
plant Radix Astragali with anti-inflammatory, antioxidant, anti-apoptotic, and liver-protecting …

Oxyresveratrol ameliorates nonalcoholic fatty liver disease by regulating hepatic lipogenesis and fatty acid oxidation through liver kinase B1 and AMP-activated …

JH Lee, SY Baek, EJ Jang, SK Ku, KM Kim… - Chemico-Biological …, 2018 - Elsevier
Oxyresveratrol (OXY) is a naturally occurring polyhydroxylated stilbene that is abundant in
mulberry wood (Morus alba L.), which has frequently been supplied as a herbal medicine. It …

[HTML][HTML] Ginsenoside Rk2, a dehydroprotopanaxadiol saponin, alleviates alcoholic liver disease via regulating NLRP3 and NLRP6 inflammasome signaling pathways …

J Zou, R Yang, R Feng, J Liu, JB Wan - Journal of Pharmaceutical Analysis, 2023 - Elsevier
Heavy alcohol consumption results in alcoholic liver disease (ALD) with inadequate
therapeutic options. Here, we first report the potential beneficial effects of ginsenoside Rk2 …

Diallyl disulfide ameliorates ethanol-induced liver steatosis and inflammation by maintaining the fatty acid catabolism and regulating the gut-liver axis

SX Liu, H Liu, S Wang, CL Zhang, FF Guo… - Food and Chemical …, 2022 - Elsevier
Diallyl disulfide (DADS) has been suggested to possess hepatoprotection against alcoholic
liver disease (ALD) by a couple of pilot studies, while the underlying mechanisms remain …

[HTML][HTML] Eriodictyol downregulates UBA52 to promote autophagy and upregulates Nrf2/HO-1 to inhibit oxidative stress to ameliorate non-alcoholic fatty liver disease

Y Cai, L Yuan, K Wang, Q Liu, H Xing, P Zhong… - Journal of Functional …, 2024 - Elsevier
Eriodictyol (Eri) is a widely distributed flavonoid compound. We explored the effect of Eri on
non-alcoholic fatty liver disease (NAFLD) and the underlying mechanism. Eri reduced …