Apigenin inhibits d-galactosamine/LPS-induced liver injury through upregulation of hepatic Nrf-2 and PPARγ expressions in mice

RJ Zhou, H Ye, F Wang, JL Wang, ML Xie - Biochemical and biophysical …, 2017 - Elsevier
Apigenin is a natural flavonoid compound widely distributed in a variety of vegetables,
medicinal plants and health foods. This study aimed to examine the protective effect of …

[HTML][HTML] Involvement of HO-1 and autophagy in the protective effect of magnolol in hepatic steatosis-induced NLRP3 inflammasome activation in vivo and in vitro

NC Kuo, SY Huang, CY Yang, HH Shen, YM Lee - Antioxidants, 2020 - mdpi.com
Magnolol (MG) is the main active compound of Magnolia officinalis and exerts a wide range
of biological activities. In this study, we investigated the effects of MG using tyloxapol (Tylo) …

[HTML][HTML] Kaempferol and nicotiflorin ameliorated alcohol-induced liver injury in mice by miR-138-5p/SIRT1/FXR and gut microbiota

J Ge, G Li, Z Chen, W Xu, X Lei, S Zhu - Heliyon, 2024 - cell.com
Aims Excessive alcohol consumption can lead to alcoholic liver diseases (ALDs).
Tetrastigma hemsleyanum Diels et Gilg is a rare Chinese medicinal herb. Tetrastigma …

[HTML][HTML] Maltol, a food flavoring agent, attenuates acute alcohol-induced oxidative damage in mice

Y Han, Q Xu, J Hu, X Han, W Li, L Zhao - Nutrients, 2015 - mdpi.com
The purpose of this study was to evaluate the hepatoprotective effect of maltol, a food-
flavoring agent, on alcohol-induced acute oxidative damage in mice. Maltol used in this …

1-O-Actylbritannilactone Ameliorates Alcohol-Induced Hepatotoxicity through Regulation of ROS/Akt/NF-κB-Mediated Apoptosis and Inflammation

L Xie, Z Yang, Y Wang, J Hu, Y Lu, H Zhang, S Jiang… - ACS …, 2022 - ACS Publications
1-O-Acetylbritannilactone (ABL) is a marker component of Inula britannica L. and is reported
to exhibit multiple pharmacological activities, including antiaging, anti-inflammatory, and …

[HTML][HTML] Oleoylethanolamide protects against acute liver injury by regulating Nrf-2/HO-1 and NLRP3 pathways in mice

J Hu, Z Zhu, H Ying, J Yao, H Ma, L Li… - Frontiers in …, 2021 - frontiersin.org
Acute liver injury is a rapidly deteriorating clinical condition with markedly high morbidity and
mortality. Oleoylethanolamide (OEA) is an endogenous lipid messenger with multiple …

Glycyrrhetinic acid prevents acetaminophen-induced acute liver injury via the inhibition of CYP2E1 expression and HMGB1-TLR4 signal activation in mice

G Yang, L Zhang, L Ma, R Jiang, G Kuang, K Li… - International …, 2017 - Elsevier
Acetaminophen (APAP) is a widely used antipyretic and analgesic drug, which is safe and
effective at the therapeutic dose. Unfortunately, excessive dosage of APAP could cause …

Nobiletin ameliorates hepatic lipid deposition, oxidative stress, and inflammation by mechanisms that involve the Nrf2/NF-κB Axis in nonalcoholic fatty liver disease

C Fan, A Ling-Hu, D Sun, W Gao, C Zhang… - Journal of Agricultural …, 2023 - ACS Publications
Nobiletin (NOB), a flavonoid with significant antioxidant potential, holds promise for treating
nonalcoholic fatty liver disease (NAFLD). In this work, we aim to assess the effects and …

[HTML][HTML] Salidroside regulates inflammatory response in raw 264.7 macrophages via TLR4/TAK1 and ameliorates inflammation in alcohol binge drinking-induced liver …

P Sun, SZ Song, S Jiang, X Li, YL Yao, YL Wu, LH Lian… - Molecules, 2016 - mdpi.com
The current study was designed to investigate the anti-inflammatory effect of salidroside
(SDS) and the underlying mechanism by using lipopolysaccharide (LPS)-stimulated RAW …

Aronia melanocarpa Prevents Alcohol‐Induced Chronic Liver Injury via Regulation of Nrf2 Signaling in C57BL/6 Mice

Z Wang, Y Liu, X Zhao, S Liu, Y Liu… - Oxidative Medicine and …, 2020 - Wiley Online Library
Aronia melanocarpa (AM), which is rich in anthocyanins and procyanidins, has been
reported to exert antioxidative and anti‐inflammatory effects. This study aimed to …