Shanxi aged vinegar protects against alcohol-induced liver injury via activating Nrf2-mediated antioxidant and inhibiting TLR4-induced inflammatory response

T Xia, J Zhang, J Yao, B Zhang, W Duan, C Zhao, P Du… - Nutrients, 2018 - mdpi.com
Shanxi aged vinegar (SAV) is a typical fermented and antioxidant food, which has various
health-promoting effects. This work aimed to explore the effects of SAV on alcohol-induced …

P-hydroxyacetophenone ameliorates alcohol-induced steatosis and oxidative stress via the NF-κB signaling pathway in zebrafish and hepatocytes

S Huang, C Zhou, T Zeng, Y Li, Y Lai, C Mo… - Frontiers in …, 2020 - frontiersin.org
Alcoholic liver disease (ALD), which is recognized as an important health problem
worldwide, is a direct consequence of alcohol consumption, which can induce alcoholic fatty …

Astragaloside IV attenuates acetaminophen-induced liver injuries in mice by activating the Nrf2 signaling pathway

L Li, W Huang, S Wang, K Sun, W Zhang, Y Ding… - Molecules, 2018 - mdpi.com
Acetaminophen (APAP) is a well-known antipyretic and analgesic drug. However, the
accidental or intentional APAP overdose will induce liver injury and even acute liver failure …

Ginsenoside Rg3 ameliorates acetaminophen-induced hepatotoxicity by suppressing inflammation and oxidative stress

Y Gao, J Yan, J Li, X Li, S Yang, N Chen… - Journal of Pharmacy …, 2021 - academic.oup.com
Objectives Improper usage of acetaminophen (APAP) leads to morbidity and also mortality
secondary to liver damage. Ginseng could suppress APAP-induced hepatotoxicity and …

Baicalin ameliorates liver injury induced by chronic plus binge ethanol feeding by modulating oxidative stress and inflammation via CYP2E1 and NRF2 in mice

P He, Y Wu, J Shun, Y Liang, M Cheng… - … Medicine and Cellular …, 2017 - Wiley Online Library
Alcoholic liver injury leads to serious complication including death. The potential role of
baicalin at the transcription level in mice model of alcohol injury is not known yet. In this …

Preventive effects of indole-3-carbinol against alcohol-induced liver injury in mice via antioxidant, anti-inflammatory, and anti-apoptotic mechanisms: Role of gut-liver …

Y Choi, MA Abdelmegeed, BJ Song - The Journal of Nutritional …, 2018 - Elsevier
Abstract Indole-3-carbinol (I3C), found in Brassica family vegetables, exhibits antioxidant,
anti-inflammatory, and anti-cancerous properties. Here, we aimed to evaluate the preventive …

Nuciferine alleviates acute alcohol-induced liver injury in mice: Roles of suppressing hepatic oxidative stress and inflammation via modulating miR-144/Nrf2/HO-1 …

G Shu, Y Qiu, J Hao, Q Fu, X Deng - Journal of Functional Foods, 2019 - Elsevier
Binge consumption of alcohol results in severe global health problem. This study aimed to
explore the potential efficacy of nuciferine (NCF) in protecting acute alcohol-induced liver …

Caffeine inhibits NLRP3 inflammasome activation by downregulating TLR4/MAPK/NF-κB signaling pathway in an experimental NASH model

EE Vargas-Pozada, E Ramos-Tovar… - International Journal of …, 2022 - mdpi.com
Caffeine elicits protective effects against liver diseases, such as NASH; however, its
mechanism of action involving the pyrin domain-containing-3 (NLRP3) inflammasome …

Resveratrol improves alcoholic fatty liver disease by downregulating HIF-1α expression and mitochondrial ROS production

Z Ma, Y Zhang, Q Li, M Xu, J Bai, S Wu - PloS one, 2017 - journals.plos.org
Oxidative stress has been demonstrated to be involved in the etiology of alcoholic fatty liver
disease (AFLD). Previous studies had demonstrated that resveratrol (RES) could reduce …

LanGui tea, an herbal medicine formula, protects against binge alcohol-induced acute liver injury by activating AMPK-NLRP3 signaling

M Gu, Y Chen, Y Feng, Z Tang - Chinese Medicine, 2024 - Springer
Background LanGui tea, a traditional Chinese medicine formulation comprising of
Gynostemma pentaphyllum (Thunb.) Makino, Cinnamomum cassia (L.) J. Presl, and …