Aims Demethylenetetrahydroberberine (DMTHB) is a novel derivative of berberine and
demethyleneberberine. This research explored the pharmacological effects and molecular …

Alcoholic liver disease (ALD) is a major etiology of liver diseases, causing heavy health
burdens personally and socially. Ligustrazine has been widely used in China due to its …

Objective: To investigate the protective effects of Dendrobium nobile Lindl. alkaloids (DNLA)
against chronic alcoholic liver injury. C57BL/6J mice were fed with the Lieber–DeCarli …

Chronic alcohol consumption causes alcohol-induced lipogenesis and promotes hepatic
injury by preventing the oxidation of hepatocellular fatty acids through the suppression of the …

This study examined the effect of Asiatic acid from Potentilla chinensis (AAPC) on chronic
ethanol-induced hepatic injury. Rats underwent intragastric administration of ethanol (5.0 …

Alcohol-related liver disease (ALD) is a major cause of chronic liver disease worldwide with
limited therapeutic options. Here, we first revealed the promising beneficial effect of gut …

Background Acetaminophen (APAP) is a worldwide antipyretic as well as an analgesic
medication. It has been extensively utilized during the outbreak of coronavirus 2019 (COVID …

Objective: Hydroxytyrosol (HT) is a polyphenol with a wide range of biological activities.
Excessive drinking can lead to oxidative stress and inflammation in the liver, which usually …

Much research has indicated that alcoholic liver disease (ALD) is associated with oxidative
stress and inflammation induced by ethanol, and that numerous antioxidants could …

Metabolic associated fatty liver disease (MAFLD) is one of the most common chronic liver
diseases and may develop into non-alcoholic steatohepatitis (NASH), fibrosis, cirrhosis, and …