Species fractionation in a case-control study concerning Parkinson's disease: Cu-amino acids discriminate CSF of PD from controls

D Willkommen, M Lucio, P Schmitt-Kopplin… - Journal of Trace …, 2018 - Elsevier
Background Parkinson's disease is affecting about 1% of the population above 65 years.
Improvements in medicine support prolonged lifetime which increases the total …

Trace and major elements in whole blood, serum, cerebrospinal fluid and urine of patients with Parkinson's disease

G Forte, B Bocca, O Senofonte, F Petrucci… - Journal of neural …, 2004 - Springer
Quantifications of Al, Ca, Cu, Fe, Mg, Mn, Si and Zn were performed in urine, serum, blood
and cerebrospinal fluid (CSF) of 26 patients affected by Parkinson's disease (PD) and 13 …

Elemental profile of cerebrospinal fluid in patients with Parkinson's disease

A Alimonti, B Bocca, A Pino, F Ruggieri, G Forte… - Journal of Trace …, 2007 - Elsevier
To ascertain the potential role of chemical elements (namely, Al, Ba, Be, Bi, Ca, Cd, Co, Cr,
Cu, Fe, Hg, Li, Mg, Mn, Mo, Ni, Pb, Sb, Si, Sn, Sr, Tl, V, W, Zn and Zr) as markers in the …

Assessment of copper, iron, zinc and manganese status and speciation in patients with Parkinson's disease: A pilot study

OP Ajsuvakova, AA Tinkov, D Willkommen… - Journal of Trace …, 2020 - Elsevier
Background The objective of this pilot study was to assess iron (Fe), copper (Cu), zinc (Zn),
and manganese (Mn) status (hair, serum, and urine) and speciation (serum) in Parkinson's …

Metal changes in CSF and peripheral compartments of parkinsonian patients

B Bocca, A Alimonti, O Senofonte, A Pino… - Journal of the …, 2006 - Elsevier
BACKGROUND: Involvement of metals in the risk of developing Parkinson's disease (PD)
has been suggested. In the present study, concentration of metals in cerebrospinal fluid …

Quantification of trace elements by sector field inductively coupled plasma mass spectrometry in urine, serum, blood and cerebrospinal fluid of patients with …

B Bocca, A Alimonti, F Petrucci, N Violante… - … Acta Part B: Atomic …, 2004 - Elsevier
To assess whether levels of trace metals and oxidative species are involved in Parkinson's
disease (PD), Al, Be, Cd, Co, Cr, Hg, Mn, Ni, Pb and V were measured in urine, serum, blood …

[HTML][HTML] Simultaneous quantification and speciation of trace metals in paired serum and CSF samples by size exclusion chromatography–inductively coupled plasma …

B Michalke, A Berthele, V Venkataramani - International journal of …, 2021 - mdpi.com
Background: Transition metals play a crucial role in brain metabolism: since they exist in
different oxidation states they are involved in ROS generation, but they are also co-factors of …

Review on metal speciation analysis in cerebrospinal fluid—current methods and results: A review

B Michalke, V Nischwitz - Analytica chimica acta, 2010 - Elsevier
The large number of patients suffering from neurodegenerative diseases like Alzheimer's
disease and Parkinson's disease motivates many research groups worldwide to investigate …

Patterns of levels of biological metals in CSF differ among neurodegenerative diseases

I Hozumi, T Hasegawa, A Honda, K Ozawa… - Journal of the …, 2011 - Elsevier
We measured the levels of some biological metals: copper (Cu), iron (Fe), magnesium (Mg),
manganese (Mn), and zinc (Zn) in the cerebrospinal fluid (CSF) in patients with …

Relationship between blood levels of heavy metals and Parkinson's disease in China

T Fukushima, X Tan, Y Luo, H Kanda - Neuroepidemiology, 2010 - karger.com
Abstract Background: Idiopathic Parkinson's disease (PD) and the Parkinsonian syndrome
caused by manganese (Mn) poisoning are known to be indistinguishable in terms of …