Immunohistochemical localization of oxytocin receptors in human brain
ML Boccia, P Petrusz, K Suzuki, L Marson… - Neuroscience, 2013 - Elsevier
The neuropeptide oxytocin (OT) regulates rodent, primate and human social behaviors and
stress responses. OT binding studies employing 125 Id (CH 2) 5-[Tyr (Me) 2, Thr 4, Tyr-NH 2 …
stress responses. OT binding studies employing 125 Id (CH 2) 5-[Tyr (Me) 2, Thr 4, Tyr-NH 2 …
Switching brain serotonin with oxytocin
Serotonin (5-HT) and oxytocin (OXT) are two neuromodulators involved in human affect and
sociality and in disorders like depression and autism. We asked whether these chemical …
sociality and in disorders like depression and autism. We asked whether these chemical …
Homo‐and hetero‐dimeric complex formations of the human oxytocin receptor
D Devost, HH Zingg - Journal of neuroendocrinology, 2004 - Wiley Online Library
Using two different coimmunoprecipitation strategies as well as bioluminescence resonance
energy transfer (BRET) techniques, we determined that the human oxytocin receptor forms …
energy transfer (BRET) techniques, we determined that the human oxytocin receptor forms …
Roles of the oxytocin receptor (OXTR) in human diseases
K Pierzynowska, L Gaffke, M Żabińska, Z Cyske… - International journal of …, 2023 - mdpi.com
The oxytocin receptor (OXTR), encoded by the OXTR gene, is responsible for the signal
transduction after binding its ligand, oxytocin. Although this signaling is primarily involved in …
transduction after binding its ligand, oxytocin. Although this signaling is primarily involved in …
Allosteric interactions between the oxytocin receptor and the β2-adrenergic receptor in the modulation of ERK1/2 activation are mediated by heterodimerization
PK Wrzal, D Devost, D Pétrin, E Goupil, C Iorio-Morin… - Cellular signalling, 2012 - Elsevier
The oxytocin receptor (OTR) and the β2-adrenergic receptor (β2AR) are key regulators of
uterine contraction. These two receptors are targets of tocolytic agents used to inhibit pre …
uterine contraction. These two receptors are targets of tocolytic agents used to inhibit pre …
[HTML][HTML] Oxytocin receptor ligand binding in embryonic tissue and postnatal brain development of the C57BL/6J mouse
EAD Hammock, P Levitt - Frontiers in behavioral neuroscience, 2013 - frontiersin.org
Oxytocin (OXT) has drawn increasing attention as a developmentally relevant neuropeptide
given its role in the brain regulation of social behavior. It has been suggested that OXT plays …
given its role in the brain regulation of social behavior. It has been suggested that OXT plays …
Non-peptide oxytocin agonists
G Pitt, A Batt, R Haigh, A Penson, P Robson… - Bioorganic & medicinal …, 2004 - Elsevier
A library of compounds targeted to the vasopressin/oxytocin family of receptors was
screened for activity at a cloned human oxytocin receptor using a reporter gene assay …
screened for activity at a cloned human oxytocin receptor using a reporter gene assay …
[HTML][HTML] Oxytocin and social motivation
Humans are fundamentally social creatures who are 'motivated'to be with others. In this
review we examine the role of oxytocin (OT) as it relates to social motivation. OT is …
review we examine the role of oxytocin (OT) as it relates to social motivation. OT is …
Sex differences in the embryonic development of the central oxytocin system in mice
S Tamborski, EM Mintz… - Journal of …, 2016 - Wiley Online Library
Recent studies suggest that oxytocin (OXT) may be important for organising the neural
circuitry that underlies adult social behaviour. Although most of the work exploring these …
circuitry that underlies adult social behaviour. Although most of the work exploring these …
Oxytocin as a potential mediator and modulator of drug addiction
Z Sarnyai - Addiction Biology, 2011 - researchonline.jcu.edu.au
[Extract] Oxytocin, a nine amino acid neuropeptide, first discovered by Sir Heury Dale in
1906, is a potent modulator of a variety of brain functions including emotions, mood, social …
1906, is a potent modulator of a variety of brain functions including emotions, mood, social …