Antibody-dependent cytolytically active human leukocytes: an analysis of inactivation following in vitro interaction with antibody-coated target cells

HK Ziegler, CS Henney - Journal of Immunology, 1975 - journals.aai.org
A leukocyte population consisting of approximately 85% lymphocytes, prepared from human
peripheral blood by centrifugation through a Ficoll-Hypaque gradient, was studied for its …

Effector cell activity in antibody mediated cell dependent immune lysis: II. Evidence for different populations of effector cells for different targets

T Kovithavongs, G Rice, KL Thong, JB Dossetor - Cellular Immunology, 1975 - Elsevier
Using the adhering property of certain types of cells to glass or plastic in human peripheral
blood lymphocyte preparations, two populations of effector cells can be identified in the …

Antibody‐mediated target cell lysis by non‐immune cells. Characterization of the antibody and effector cell populations

EW Gelfand, K Resch, M Prester - European journal of …, 1972 - Wiley Online Library
Cells from normal rabbit thymus, lymph node and spleen demonstrated in vitro cytolytic
activity when incubated with antibody‐coated target cells. High dilutions of antibody were …

Specifically cytotoxic lymphocytes produced by preincubation with antibody-complexed target cells

P Perlmann, H Perlmann, P Biberfeld - The Journal of Immunology, 1972 - journals.aai.org
Highly purified human blood lymphocytes which had been incubated with antibody-
complexed chicken erythrocytes, adsorbed 50 to 100× more of this antibody (rabbit) than …

Targeted cytotoxic cells in human peripheral blood lymphocytes.

MA Garrido, P Perez, JA Titus, MJ Valdayo… - … (Baltimore, Md.: 1950 …, 1990 - journals.aai.org
We have isolated subsets of cells from human PBL and have investigated their abilities to
mediate lysis targeted by bispecific antibodies. Targeted cytotoxic cells were divided into two …

Kinetic analysis of antibody-dependent cellular cytotoxicity: evidence for noncompetitive inhibition by autologous lymphoid cells

MV Herrick, SB Pollack - The Journal of Immunology, 1978 - journals.aai.org
Inhibition of antibody-dependent cellular cytotoxicity (ADCC) by autologous lymphocytes
was analyzed by using classical techniques for enzyme-substrate interactions. We …

Antibody-dependent cell-mediated cytolysis (ADCC) with antibody-coated effectors: new methods for enhancing antibody binding and cytolysis.

JF Jones, DM Segal - Journal of immunology (Baltimore, Md.: 1950), 1980 - journals.aai.org
When P388D1 cells are incubated with anti-TNP IgG antibody and centrifuged through a
mixture of dibutylphthalate and bis-(2-ethylhexyl) phthalate (1.5: 1), large amounts of …

Antibody‐dependent cell‐mediated cytotoxicity: Heterogeneity of effector cells in human peripheral blood

HR MacDonald, GD Bonnard, B Sordat… - Scandinavian …, 1975 - Wiley Online Library
We have compared antibody‐dependent cell‐mediated cytotoxicity (ADCMC) of human
peripheral blood leukocytes (PBL) in three model systems Target cells were 51Cr‐labeled …

Potentiation of the cytolytic activity of peripheral blood monocytes by lymphokines and interferon.

DG Fischer, MG Golightly, HS Koren - Journal of immunology …, 1983 - journals.aai.org
Human peripheral blood monocytes obtained by EDTA-reversible adherence to plastic
surfaces precoated with autologous serum can rapidly lyse a variety of tumor cells. That the …

The antibody-dependent cell-mediated cytotoxic reaction. II. The effect of the concentration of anti-target cell antibodies on the identity of the human effector cells.

M Keaney, S McPhail, CA Jodouín, M Richter - Immunology, 1980 - ncbi.nlm.nih.gov
The circulating leucocytes of normal adults (lymphocytes, monocyte-lymphocyte mixtures
and neutrophils) were investigated for their capacity to induce antibody-dependent cell …