Macroautophagy/autophagy, a highly conserved lysosome-dependent degradation
pathway, has been intensively studied in regulating cell metabolism by degradation of …

Cancer remains the second leading cause of death worldwide and a major public health
and economic issue. To reduce the burden, new approaches are necessary to diagnose the …

Dysregulated autophagy is central to the pathogenesis and therapeutic development of
cancer. However, how autophagy is regulated in cancer is not well understood and genes …

Autophagy, a complex and highly regulated cellular process, is critical for the maintenance
of cellular homeostasis by lysosomal degradation of cellular debris, intracellular pathogens …

Macroautophagy/autophagy is a conserved catabolic pathway that is vital for maintaining
cell homeostasis and promoting cell survival under stressful conditions. Dysregulation of …

Various metabolic pathways and molecular processes in the cell act intertwined, and
dysregulating the interplay between some of them may lead to cancer. It is only recently that …

Autophagy (macroautophagy) is an evolutionarily conserved lysosomal degradation
process, in which a cell degrades long-lived proteins and damaged organelles. Recently …

Autophagy is an evolutionarily conserved catabolic process that is induced in response to
various stress factors in order to protect cells and maintain cellular homeostasis by …

Autophagy is a lysosomal degradation pathway that depends on various evolutionarily
conserved autophagy-related genes (ATGs). Dysregulation of autophagy plays an important …

Autophagy is an essential cellular mechanism which plays “housekeeping” role in normal
physiological processes including removing of long lived, aggregated and misfolded …