Causes and consequences of DNA damage-induced autophagy

T Juretschke, P Beli - Matrix Biology, 2021 - Elsevier
Autophagy is a quality control pathway that maintains cellular homeostasis by recycling
surplus and dysregulated cell organelles. Identification of selective autophagy receptors …

[HTML][HTML] MicroRNAs as major regulators of the autophagy pathway

Y Akkoc, D Gozuacik - Biochimica et Biophysica Acta (BBA)-Molecular Cell …, 2020 - Elsevier
Autophagy is a cellular stress response mechanism activation of which leads to degradation
of cellular components, including proteins as well as damaged organelles in lysosomes …

[HTML][HTML] Non-coding RNAs as new autophagy regulators in cancer progression

Q Lin, Y Shi, Z Liu, M Mehrpour, A Hamaï… - Biochimica et Biophysica …, 2022 - Elsevier
Recent advances highlight that non-coding RNAs (ncRNAs) are emerging as fundamental
regulators in various physiological as well as pathological processes by regulating macro …

Autophagy and cancer cell metabolism

F Lozy, V Karantza - Seminars in cell & developmental biology, 2012 - Elsevier
Autophagy is a catabolic process involving lysosomal turnover of proteins and organelles for
maintenance of cellular homeostasis and mitigation of metabolic stress. Autophagy defects …

Mechanisms of selective autophagy in normal physiology and cancer

JD Mancias, AC Kimmelman - Journal of molecular biology, 2016 - Elsevier
Selective autophagy is critical for regulating cellular homeostasis by mediating lysosomal
turnover of a wide variety of substrates including proteins, aggregates, organelles, and …

Long non-coding RNAs involved in autophagy regulation

L Yang, H Wang, Q Shen, L Feng, H Jin - Cell death & disease, 2017 - nature.com
Autophagy degrades non-functioning or damaged proteins and organelles to maintain
cellular homeostasis in a physiological or pathological context. Autophagy can be protective …

Autophagy roles in genome maintenance

S Ambrosio, B Majello - Cancers, 2020 - mdpi.com
In recent years, a considerable correlation has emerged between autophagy and genome
integrity. A range of mechanisms appear to be involved where autophagy participates in …

Autophagy: an emerging target for cancer therapy

M Høyer-Hansen, M Jäättelä - Autophagy, 2008 - Taylor & Francis
Macroautophagy (hereafter referred to as autophagy) is a lysosomal catabolic pathway
whereby cells recycle macromolecules and organelles. The capacity of autophagy to …

Regulatory effects of lncRNAs and miRNAs on autophagy in malignant tumorigenesis

Q Yin, W Feng, X Shen, S Ju - Bioscience Reports, 2018 - portlandpress.com
Autophagy is an important process in endogenous substrate degradation by lysosomes
within cells, with a degree of evolutionary conservation. Like apoptosis and cell senescence …

Dual role of autophagy in hallmarks of cancer

SS Singh, S Vats, AYQ Chia, TZ Tan, S Deng, MS Ong… - Oncogene, 2018 - nature.com
Evolutionarily conserved across eukaryotic cells, macroautophagy (herein autophagy) is an
intracellular catabolic degradative process targeting damaged and superfluous cellular …