Causes and consequences of DNA damage-induced autophagy
T Juretschke, P Beli - Matrix Biology, 2021 - Elsevier
Autophagy is a quality control pathway that maintains cellular homeostasis by recycling
surplus and dysregulated cell organelles. Identification of selective autophagy receptors …
surplus and dysregulated cell organelles. Identification of selective autophagy receptors …
[HTML][HTML] MicroRNAs as major regulators of the autophagy pathway
Y Akkoc, D Gozuacik - Biochimica et Biophysica Acta (BBA)-Molecular Cell …, 2020 - Elsevier
Autophagy is a cellular stress response mechanism activation of which leads to degradation
of cellular components, including proteins as well as damaged organelles in lysosomes …
of cellular components, including proteins as well as damaged organelles in lysosomes …
[HTML][HTML] Non-coding RNAs as new autophagy regulators in cancer progression
Q Lin, Y Shi, Z Liu, M Mehrpour, A Hamaï… - Biochimica et Biophysica …, 2022 - Elsevier
Recent advances highlight that non-coding RNAs (ncRNAs) are emerging as fundamental
regulators in various physiological as well as pathological processes by regulating macro …
regulators in various physiological as well as pathological processes by regulating macro …
Autophagy and cancer cell metabolism
F Lozy, V Karantza - Seminars in cell & developmental biology, 2012 - Elsevier
Autophagy is a catabolic process involving lysosomal turnover of proteins and organelles for
maintenance of cellular homeostasis and mitigation of metabolic stress. Autophagy defects …
maintenance of cellular homeostasis and mitigation of metabolic stress. Autophagy defects …
Mechanisms of selective autophagy in normal physiology and cancer
JD Mancias, AC Kimmelman - Journal of molecular biology, 2016 - Elsevier
Selective autophagy is critical for regulating cellular homeostasis by mediating lysosomal
turnover of a wide variety of substrates including proteins, aggregates, organelles, and …
turnover of a wide variety of substrates including proteins, aggregates, organelles, and …
Long non-coding RNAs involved in autophagy regulation
Autophagy degrades non-functioning or damaged proteins and organelles to maintain
cellular homeostasis in a physiological or pathological context. Autophagy can be protective …
cellular homeostasis in a physiological or pathological context. Autophagy can be protective …
Autophagy roles in genome maintenance
S Ambrosio, B Majello - Cancers, 2020 - mdpi.com
In recent years, a considerable correlation has emerged between autophagy and genome
integrity. A range of mechanisms appear to be involved where autophagy participates in …
integrity. A range of mechanisms appear to be involved where autophagy participates in …
Autophagy: an emerging target for cancer therapy
M Høyer-Hansen, M Jäättelä - Autophagy, 2008 - Taylor & Francis
Macroautophagy (hereafter referred to as autophagy) is a lysosomal catabolic pathway
whereby cells recycle macromolecules and organelles. The capacity of autophagy to …
whereby cells recycle macromolecules and organelles. The capacity of autophagy to …
Regulatory effects of lncRNAs and miRNAs on autophagy in malignant tumorigenesis
Q Yin, W Feng, X Shen, S Ju - Bioscience Reports, 2018 - portlandpress.com
Autophagy is an important process in endogenous substrate degradation by lysosomes
within cells, with a degree of evolutionary conservation. Like apoptosis and cell senescence …
within cells, with a degree of evolutionary conservation. Like apoptosis and cell senescence …
Dual role of autophagy in hallmarks of cancer
Evolutionarily conserved across eukaryotic cells, macroautophagy (herein autophagy) is an
intracellular catabolic degradative process targeting damaged and superfluous cellular …
intracellular catabolic degradative process targeting damaged and superfluous cellular …