Autophagy: cellular and molecular mechanisms
D Glick, S Barth, KF Macleod - The Journal of pathology, 2010 - Wiley Online Library
Autophagy is a self‐degradative process that is important for balancing sources of energy at
critical times in development and in response to nutrient stress. Autophagy also plays a …
critical times in development and in response to nutrient stress. Autophagy also plays a …
Autophagy in disease: a double-edged sword with therapeutic potential
W Martinet, P Agostinis, B Vanhoecke… - Clinical …, 2009 - portlandpress.com
Autophagy is a catabolic trafficking pathway for bulk destruction and turnover of long-lived
proteins and organelles via regulated lysosomal degradation. In eukaryotic cells, autophagy …
proteins and organelles via regulated lysosomal degradation. In eukaryotic cells, autophagy …
The emerging role of oxidative stress in regulating autophagy: applications of cancer therapy
W Zhang, X Wan, Z Liu, L Xiao, H Huang… - Cellular and Molecular …, 2017 - cellmolbiol.org
Emerging evidences show that autophagy, as a major cellular adaptive degradation
mechanism, is involved in tumorigenesis, cell aging, inflammation and neurodegeneration. It …
mechanism, is involved in tumorigenesis, cell aging, inflammation and neurodegeneration. It …
Autophagy role (s) in response to oncogenes and DNA replication stress
R Vanzo, J Bartkova, JM Merchut-Maya, A Hall… - Cell Death & …, 2020 - nature.com
Autophagy is an evolutionarily conserved process that captures aberrant intracellular
proteins and/or damaged organelles for delivery to lysosomes, with implications for cellular …
proteins and/or damaged organelles for delivery to lysosomes, with implications for cellular …
Transcriptional regulation of autophagy: mechanisms and diseases
C Di Malta, L Cinque, C Settembre - Frontiers in cell and …, 2019 - frontiersin.org
Macro (Autophagy) is a catabolic process that relies on the cooperative function of two
organelles: the lysosome and the autophagosome. The recent discovery of a transcriptional …
organelles: the lysosome and the autophagosome. The recent discovery of a transcriptional …
Here, There Be Dragons: Charting Autophagy-Related Alterations in Human Tumors
CB Lebovitz, SB Bortnik, SM Gorski - Clinical Cancer Research, 2012 - AACR
Macroautophagy (or autophagy) is a catabolic cellular process that is both homeostatic and
stress adaptive. Normal cells rely on basal levels of autophagy to maintain cellular integrity …
stress adaptive. Normal cells rely on basal levels of autophagy to maintain cellular integrity …
Epigenetic regulation of autophagy beyond the cytoplasm: a review
Y Shi, HM Shen, V Gopalakrishnan… - Frontiers in Cell and …, 2021 - frontiersin.org
Autophagy is a highly conserved catabolic process induced under various stress conditions
to protect the cell from harm and allow survival in the face of nutrient-or energy-deficient …
to protect the cell from harm and allow survival in the face of nutrient-or energy-deficient …
Autophagy—from molecular mechanisms to clinical relevance
M Lippai, Z Szatmári - Cell biology and toxicology, 2017 - Springer
Autophagy is a lysosomal degradation pathway of eukaryotic cells that is highly conserved
from yeast to mammals. During this process, cooperating protein complexes are recruited in …
from yeast to mammals. During this process, cooperating protein complexes are recruited in …
The emergence of noncoding RNAs as Heracles in autophagy
J Zhang, P Wang, L Wan, S Xu, D Pang - Autophagy, 2017 - Taylor & Francis
Macroautophagy/autophagy is a catabolic process that is widely found in nature. Over the
past few decades, mounting evidence has indicated that noncoding RNAs, ranging from …
past few decades, mounting evidence has indicated that noncoding RNAs, ranging from …
Autophagy and tumorigenesis
M Rangel, J Kong, V Bhatt, K Khayati… - The FEBS …, 2022 - Wiley Online Library
Autophagy is a catabolic process that captures cellular waste and degrades them in the
lysosome. The main functions of autophagy are quality control of cytosolic proteins and …
lysosome. The main functions of autophagy are quality control of cytosolic proteins and …