Biodegradable MnO-based nanoparticles with engineering surface for tumor therapy: simultaneous fenton-like ion delivery and immune activation
Z Sun, Z Wang, T Wang, J Wang, H Zhang, Z Li… - ACS …, 2022 - ACS Publications
Immune checkpoint inhibitors have achieved significant clinical success but are still suffering
from inadequate immune activation. It is worth noting that manganese as a nutritional …
from inadequate immune activation. It is worth noting that manganese as a nutritional …
Biomineralized MnO2 Nanoplatforms Mediated Delivery of Immune Checkpoint Inhibitors with STING Pathway Activation to Potentiate Cancer Radio-Immunotherapy
Radiotherapy (RT), as one of the main methods in the clinical treatment of various malignant
tumors, would induce systemic immunotherapeutic effects by triggering immunogenic cell …
tumors, would induce systemic immunotherapeutic effects by triggering immunogenic cell …
Manganese-Enriched Zinc Peroxide Functional Nanoparticles for Potentiating Cancer Immunotherapy
M Zhou, S Liang, D Liu, K Ma, K Yun, J Yao, Y Peng… - Nano Letters, 2023 - ACS Publications
Immunotherapies have shown high clinical success, however, the therapeutical efficacy is
largely restrained by insufficient immune activation and an immunosuppressive …
largely restrained by insufficient immune activation and an immunosuppressive …
Manganese Dioxide-Entrapping Dendrimers Co-Deliver Protein and Nucleotide for Magnetic Resonance Imaging-Guided Chemodynamic/Starvation/Immune Therapy …
Y Gao, Z Ouyang, S Shen, H Yu, B Jia, H Wang… - ACS …, 2023 - ACS Publications
Development of a nanoscale drug delivery system that can simultaneously exert efficient
tumor therapeutic efficacy while creating the desired antitumor immune responses is still …
tumor therapeutic efficacy while creating the desired antitumor immune responses is still …
Manganese‐based tumor immunotherapy
K Zhang, C Qi, K Cai - Advanced Materials, 2023 - Wiley Online Library
As an essential micronutrient, manganese (Mn) participates in various physiological
processes and plays important roles in host immune system, hematopoiesis, endocrine …
processes and plays important roles in host immune system, hematopoiesis, endocrine …
Manganese-Based Nanoactivator Optimizes Cancer Immunotherapy via Enhancing Innate Immunity
L Hou, C Tian, Y Yan, L Zhang, H Zhang, Z Zhang - ACS nano, 2020 - ACS Publications
Cyclic GMP-AMP synthase (cGAS) and stimulator of interferon genes (STING) are essential
components of the innate immune sensors to cytosolic DNA and elicit type I interferon (IFN) …
components of the innate immune sensors to cytosolic DNA and elicit type I interferon (IFN) …
Multifunctional Calcium–Manganese Nanomodulator Provides Antitumor Treatment and Improved Immunotherapy via Reprogramming of the Tumor Microenvironment
G Luo, X Li, J Lin, G Ge, J Fang, W Song, GG Xiao… - ACS …, 2023 - ACS Publications
Ions play a vital role in regulating various biological processes, including metabolic and
immune homeostasis, which involves tumorigenesis and therapy. Thus, the perturbation of …
immune homeostasis, which involves tumorigenesis and therapy. Thus, the perturbation of …
A nano “Immune‐Guide” recruiting lymphocytes and modulating the ratio of macrophages from different origins to enhance cancer immunotherapy
W Sun, J Yang, M Hou, S Xie, L Xiong… - Advanced Functional …, 2021 - Wiley Online Library
Artificially modulating the type, density, and location of immune cells within the tumor
microenvironment can suppress tumor growth and efficiently promote current …
microenvironment can suppress tumor growth and efficiently promote current …
[HTML][HTML] Manganese molybdate nanodots with dual amplification of STING activation for “cycle” treatment of metalloimmunotherapy
Certain types of cationic metal ions, such as Mn 2+ are able to activate immune functions via
the stimulator of interferon genes (STING) pathway, showing potential applications in …
the stimulator of interferon genes (STING) pathway, showing potential applications in …
Versatile octapod-shaped hollow porous manganese (II) oxide nanoplatform for real-time visualization of cargo delivery
R Wei, X Gong, H Lin, K Zhang, A Li, K Liu, H Shan… - Nano …, 2019 - ACS Publications
Multifunctional nanoplatforms featuring promising properties including excellent loading
efficiency, real-time monitoring, and improved cargo bioavailability and bioselectivity are in …
efficiency, real-time monitoring, and improved cargo bioavailability and bioselectivity are in …