Granulocytapheresis is useful as an alternative therapy in patients with steroid-refractory or-dependent ulcerative colitis

M Naganuma, S Funakoshi, A Sakuraba… - Inflammatory bowel …, 2004 - academic.oup.com
Background Recently, granulocyte and monocyte adsorption apheresis (GCAP) has been
shown to be safe and effective for active ulcerative colitis (UC). We analyzed the safety and …

[HTML][HTML] Safety and clinical efficacy of granulocyte and monocyte adsorptive apheresis therapy for ulcerative colitis

T Yamamoto, S Umegae… - World Journal of …, 2006 - ncbi.nlm.nih.gov
Active ulcerative colitis (UC) is frequently associated with infiltration of a large number of
leukocytes into the bowel mucosa. Therefore, removal of activated circulating leukocytes by …

Selective granulocyte and monocyte adsorptive apheresis as a first-line treatment for steroid naive patients with active ulcerative colitis: a prospective uncontrolled …

Y Suzuki, N Yoshimura, AR Saniabadi… - Digestive diseases and …, 2004 - Springer
Corticosteroid therapy of ulcerative colitis (UC) is associated with frequent adverse side
effects and poor quality of life. Recently, adsorptive granulocyte and monocyte/macrophage …

Granulocytapheresis in steroid-dependent and steroid-resistant patients with inflammatory bowel disease: a prospective observational study

R Sacco, A Romano, A Mazzoni… - Journal of Crohn's …, 2013 - academic.oup.com
Background: Despite the mounting importance of granulocytapheresis (GCAP) for
inflammatory bowel disease (IBD) treatment, its effectiveness in steroid-dependent (SD) and …

[HTML][HTML] Open label trial of granulocyte apheresis suggests therapeutic efficacy in chronically active steroid refractory ulcerative colitis

W Kruis, A Dignass… - World Journal of …, 2005 - ncbi.nlm.nih.gov
AIM: To study the efficacy, safety, and feasibility of a granulocyte adsorptive type apheresis
system for the treatment of patients with chronically active ulcerative colitis despite standard …

Granulocytapheresis versus methylprednisolone in patients with acute ulcerative colitis: 12‐month follow up

G Bresci, G Parisi, A Mazzoni… - Journal of …, 2008 - Wiley Online Library
Aim: To evaluate granulocytapheresis (GCAP) in active ulcerative colitis (UC), with particular
attention to the long‐term effects of such treatment. Methods: We included 80 patients with …

An open-label prospective randomized multicenter study shows very rapid remission of ulcerative colitis by intensive granulocyte and monocyte adsorptive apheresis …

A Sakuraba, S Motoya, K Watanabe… - Official journal of the …, 2009 - journals.lww.com
OBJECTIVES: Granulocyte and monocyte adsorptive apheresis (GMA) has shown efficacy in
patients with active ulcerative colitis (UC). However, with routine weekly treatment, it may …

Clinical Effectiveness of Selective Granulocyte, Monocyte Adsorptive Apheresis with the Adacolumn® Device in Ulcerative Colitis

B Habermalz, S Sauerland - Digestive diseases and sciences, 2010 - Springer
The purpose of this meta-analysis was to determine whether selective adsorptive
granulocyte and monocyte apheresis (GMA apheresis) using the Adacolumn® device can …

Leukocyte adsorptive apheresis for the treatment of active ulcerative colitis: a prospective, uncontrolled, pilot study

H Hanai, F Watanabe, K Takeuchi, T Iida… - Clinical …, 2003 - Elsevier
Background & Aims: Active ulcerative colitis (UC) is characterized by infiltration of activated
granulocytes and monocytes/macrophages (GM) within the large bowel mucosa. GM are …

Efficacy and safety of granulocyte and monocyte adsorption apheresis for ulcerative colitis: a meta-analysis

T Yoshino, H Nakase, N Minami, S Yamada… - Digestive and Liver …, 2014 - Elsevier
Background Safe and effective treatments are required for patients with ulcerative colitis. It
was suggested that granulocyte and monocyte adsorption apheresis might play an important …