The prevalence of obesity has increased dramatically in recent decades, reaching epidemic
proportions. It is becoming clear that obesity is associated not only with type 2 diabetes …

Abstract Purpose of Review Adipocytes have adapted to store energy in the form of lipid and
also secrete circulating factors called adipokines that signal to other tissues to coordinate …

The past few years have provided substantial evidence for the vital role of the local tumor
microenvironment for various aspects of tumor progression. With obesity and its …

Obesity and its associated metabolic dysregulation are established risk factors for many
cancers. However, the biologic mechanisms underlying this relationship remain …

Obesity has emerged as a major public health concern with a staggering 39% worldwide
prevalence as of 2021. Given the magnitude of the problem and considering its association …

Adipose tissue is the largest endocrine organ and an accepted contributor to overall energy
homeostasis. There is strong evidence linking increased adiposity to the development of 13 …

Overweight and obesity are health problems of epidemic proportions, increasing the risk not
only of cardiovascular disease and type 2 diabetes mellitus but also of various types of …

Growing evidence has raised the important roles of adipocytes as an active player in the
tumor microenvironment. In many tumors adipocytes are in close contact with cancer cells …

Adipocytes are one of the primary stromal cells in many tissues, and they are considered to
play an active role in the tumor microenvironment. Cancer-associated adipocytes (CAAs) …

The interactions of adipocytes with tumour cells have been extensively scrutinized. The
adipocyte's mitogenic influence on tumour cells is attributed to several hormonal, growth …