Systemic lupus erythematosus, with its broad range of clinical and
immunologicalabnormalities, continues to provide lessons relevant to research in a wider …

We identified eight patients with the lupus anticoagulant (an autoantibody acquired by some
patients with systemic lupus erythematosus), by observation of an increased activated partial …

summary In a group of 10 women with circulating lupus anticoagulant 25 intrauterine deaths
were previously documented in the nine multigravidae. The presence of lupus anticoagulant …

The so-called lupus anticoagulant is an antibody (IgG or IgM or both) that prolongs
phospholipid-dependent coagulation tests by binding to epitopes on the phospholipid …

The lupus anticoagulant was found in the plasma of 31 of 60 patients with systemic lupus
erythematosus and other connective tissue disorders (mixed connective tissue disease …

The kaolin clotting time of platelet poor plasma was used as a sensitive test for detecting the
lupus anticoagulant in mixtures of normal and patients' plasmas. Platelets were found to …

Methods In order to examine the sensitivity of various tests and reagents for the detection of
the anticoagulant, three laboratories collected plasma samples from 24 patients previously …

Approximately 2% of the patients screened in our laboratories with activated partial
thromboplastin times are found to have a lupus anticoagulant. Recognition of lupus …

This retrospective study of 295 patients extends the earlier findings of an association
between lupus anticoagulation and thrombosis by demonstrating the occurrence of …

Circulating anticoagulants are pathological substances which interfere with clottlng
mechanisms. Their characterization has always been more difficult than that for clotting …