All guidelines recommend short‐acting inhaled β2‐adrenoceptor agonists as the first‐line
drugs in acute asthma attacks and inhaled corticosteroids as the drugs of choice when …

Abstract β 2-Adrenoceptor agonist bronchodilators are widely used in the treatment of both
asthma and chronic obstructive pulmonary disease (COPD). They provide rapid and …

New long-acting beta 2-adrenoceptor agonists, formoterol and salmeterol, may soon appear
in several European countries for treatment of asthma. This review examines currently …

Inhaled β2-adrenoceptor agonists are by far the most effective and safe bronchodilators
currently available. They have not been surpassed by any other bronchodilating principle …

Conventional low doses of inhaled beta 2‐adrenoceptor agonists produce effective
bronchodilation without systemic effects. Higher doses of inhaled beta 2‐adrenoceptor …

An endogenous defect in β 2-adrenoceptors that results in impaired relaxation of airway
smooth muscle was originally proposed as a putative underlying cause of the asthmatic …

The therapeutic goal for the treatment of asthma should be to suppress bronchial mucosal
inflammation with preventive drugs such as inhaled corticosteroids, and to relieve symptoms …

The β-adrenoceptor agonists (β-agonists) have been used to relieve bronchoconstriction for
at least 5000 years. β-agonists are based on adrenaline and early forms, such as …

There is, today, general agreement that inhaled~ 2-agonists are the drugs of choice in acute
asthma attacks, both at home and in the emergency room. However, the place for~;-agonists …

Salmeterol and formoterol belong to a new class of inhaled β2‐agonists with a prolonged
duration of action. At the time these agents were introduced, there was uncertainty regarding …