Growing evidence has demonstrated that neurogenesis in the subventricular zone (SVZ) is
significantly decreased in Parkinson's disease (PD). Modulation of endogenous …

Parkinson's disease (PD) is a prevalent neurodegenerative disorder characterized by a
progressive and extensive loss of dopaminergic (DA) neurons in the substantia nigra pars …

The use of human embryonic stem cells (hESCs) to repair diseased or injured brain is
promising technology with significant humanitarian, societal and economic impact …

Research reports on de novo neurogenesis, particularly dopaminergic (DA) neurogenesis in
the adult mammalian substantia nigra (SN) remain very controversial. For this reason, we …

Mammalian neurogenesis has been demonstrated in the subventricular zone (SVZ) of the
lateral ventricles and the subgranular zone (SGZ) of the dentate gyrus in the hippocampus …

Bone marrow derived mesenchymal stem cells (BMMSCs) is a valid, definitive candidate for
repair of damaged tissues in degenerative disorders in general and neurological diseases …

Parkinson's disease is characterized by the loss of dopaminergic neurons in the substantia
nigra pars compacta, and although restoring striatal dopamine levels may improve …

Cell replacement therapy using neural stem cells (NSCs) transplantation has recently
emerged as a promising method of Parkinson's disease (PD) treatment; however, the …

Stimulation of endogenous repair in neurodegenerative diseases, such as Parkinson's
disease (PD), appears to be a novel and promising therapeutic application of stem cells …

Enhancement of neurogenesis could be a suitable treatment approach to up-regulate
dopaminergic neurons in Parkinson's disease (PD). In the present study, we focused on the …