Alterations in immune cells and mediators in the brain: it's not always neuroinflammation!

ML Estes, AK McAllister - Brain Pathology, 2014 - Wiley Online Library
Neuroinflammation was once a clearly defined term denoting pathological immune
processes within the central nervous system (CNS). Historically, this term was used to …

Neuroinflammation: an integrating overview of reactive‐Neuroimmune cell interactions in health and disease

R Kölliker-Frers, L Udovin… - Mediators of …, 2021 - Wiley Online Library
The concept of central nervous system (CNS) inflammation has evolved over the last
decades. Neuroinflammation is the response of reactive CNS components to altered …

Neuro-immune crosstalk in CNS diseases

M Kerschensteiner, E Meinl, R Hohlfeld - Neuroscience, 2009 - Elsevier
Immune cells infiltrate the CNS in many neurological diseases with a primary or secondary
inflammatory component. In the CNS, immune cells employ shared mediators to promote …

[HTML][HTML] Neuroinflammation: ways in which the immune system affects the brain

RM Ransohoff, D Schafer, A Vincent, NE Blachère… - …, 2015 - Elsevier
Neuroinflammation is the response of the central nervous system (CNS) to disturbed
homeostasis and typifies all neurological diseases. The main reactive components of the …

Basic aspects of the immunology of neuroinflammation

ES Wohleb, JP Godbout - Inflammation in psychiatry, 2013 - karger.com
Neuroinflammation is used to describe an immune-related process that occurs within the
central nervous system (CNS). The objective of this chapter is to introduce basic aspects of …

[HTML][HTML] Central nervous system:(immunological) ivory tower or not?

IA Marin, J Kipnis - Neuropsychopharmacology, 2017 - nature.com
The view of the nervous system being the victim of destructive inflammation during
autoimmunity, degeneration, or injury has been rapidly changing. Recent studies are …

Neuronal damage in brain inflammation

O Aktas, O Ullrich, C Infante-Duarte… - Archives of …, 2007 - jamanetwork.com
In contrast to traditional textbook paradigms, recent studies indicate neuronal damage in
classic neuroinflammatory diseases of the brain, such as multiple sclerosis or meningitis. In …

Inflammation in neurodegenerative diseases

S Amor, F Puentes, D Baker, P Van Der Valk - Immunology, 2010 - Wiley Online Library
Neurodegeneration, the slow and progressive dysfunction and loss of neurons and axons in
the central nervous system, is the primary pathological feature of acute and chronic …

The brain as a target of inflammation: common pathways link inflammatory and neurodegenerative diseases

F Zipp, O Aktas - Trends in neurosciences, 2006 - cell.com
Classical knowledge distinguishes between inflammatory and non-inflammatory diseases of
the brain. Either the immune system acts on the CNS and initiates a damage cascade, as in …

[HTML][HTML] An inflammation-centric view of neurological disease: beyond the neuron

SD Skaper, L Facci, M Zusso, P Giusti - Frontiers in cellular …, 2018 - frontiersin.org
Inflammation is a complex biological response fundamental to how the body deals with
injury and infection to eliminate the initial cause of cell injury and effect repair. Unlike a …