A central feature of atherosclerosis, the most prevalent chronic vascular disease and root
cause of myocardial infarction and stroke, is leukocyte accumulation in the arterial wall …

Abnormal hematopoiesis advances cardiovascular disease by generating excess
inflammatory leukocytes that attack the arteries and the heart. The bone marrow niche …

Atherosclerosis is characterized by the progressive accumulation of lipids and leukocytes in
the arterial wall. Leukocytes such as macrophages accumulate oxidized lipoproteins in the …

Cardiovascular diseases (CVDs) incidence is becoming higher. This fact is promoted by
metabolic disorders such as obesity, and aging. Atherosclerosis is the underlying cause of …

Monocytosis and neutrophilia are frequent events in atherosclerosis. These phenomena
arise from the increased proliferation of hematopoietic stem and multipotential progenitor …

Chronic inflammation is the underlying pathophysiological mechanism of atherosclerosis.
Prominent suspects being involved in atherosclerosis are lymphocytes, platelets, and …

Aims Experimental work posits that acute ischaemic events trigger haematopoietic activity,
driving monocytosis, and atherogenesis. Considering the chronic low-grade inflammatory …

Atherosclerosis, the major underlying cause of cardiovascular disease, is characterized by a
lipid-driven infiltration of inflammatory cells in large and medium arteries. Increased …

Atherosclerosis is the major cause of cardiovascular disease (CVD). Monocyte-derived
macrophages are the most abundant immune cells in atherosclerotic plaques. In patients …

The resolution of inflammation (or inflammation-resolution) is an active and highly
coordinated process. Inflammation-resolution is governed by several endogenous factors …