Despite the growing promise of bacterial therapy, due to the tumor targeting effect, in solid
tumor treatment, most conventional therapeutic bacteria exhibit pathogenicity and …

Developing new modalities that allow multidimensional therapy with optical and
immunological regulations is a challenge ahead of pharmacology and drug discovery for …

Hypoxia can increase the resistance of tumor cells to radiotherapy and chemotherapy.
However, the dense extracellular matrix, high interstitial fluid pressure, and irregular blood …

The limited penetration depth of external excitation light would remarkably impair the
therapeutic efficacy of photodynamic therapy (PDT) and its clinical utilization. Herein, we …

Unveiling biomedical functions of tumor‐resident microbiota is challenging for developing
advanced anticancer medicines. This study demonstrates that isolated intratumoral bacteria …

Live bacteria have drawn widespread interest as carriers to deliver genes and proteins into
eukaryotic cells for the treatment of various cancer types owing to their good biocompatibility …

Photodynamic therapy (PDT) and immunotherapy are considered promising methods for the
treatment of tumors. However, these treatment systems are still suffering from shortcomings …

Background: Singlet oxygen (1 O 2) has received considerable research attention in
photodynamic therapy (PDT) due to its cytotoxic solid features. However, the inherent …

There is substantial interest regarding the understanding and designing of nanoengineered
bacteria to combat various fatal diseases. Here, we report the nanoengineering of …

Tumor oxygenation level has been regarded as an attractive target to elevate the efficiency
of photodynamic therapy (PDT). Cyanobacterial photosynthesis-mediated reversal of tumor …