It is well known that unmyelinated C-fibers and small-diameter Aδ-fibers innervate the
orofacial skin, mucous membrane, orofacial muscles, teeth, tongue, and temporomandibular …

Peripheral and central sensitizations of the trigeminal nervous system are the main
mechanisms to promote the development and maintenance of chronic orofacial pain …

Objectives: This review discusses plasticity of excitatory synaptic transmission in the spinal
dorsal horn and the role of this plasticity in contributing to the pathogenesis of pain …

This article presents an overview of possible mechanisms associated with pain perception,
with a specific focus on understanding unusual manifestations of orofacial pain associated …

Previous studies indicate that the astroglial glutamate–glutamine shuttle may be involved in
acute pulpal inflammatory pain by influencing central sensitization induced in nociceptive …

The purpose of this study was to investigate the effects of jaw-muscle fatigue evoked by low-
level tooth-clenching followed by the induction of experimental muscle pain by injection of …

Recent anatomical and behavioral data show the expression of G-protein coupled
metabotropic glutamate receptors in the periphery on nociceptive primary afferent nerve …

Aims: To investigate the effects of local intramuscular injection of the N-methyl-D-aspartate
(NMDA) receptor antagonist ketamine on chronic myofascial pain and mandibular function …

With the emphasis on a neurobiologic per-spective, Dr. Svensson sets himself apart from the
traditional dental-orthopedic constructs that have stifled progress of this field. Central to the …

We assessed the trigeminal nociceptive pathways in patients with painful
temporomandibular disorders (TMD) and control subjects using a CO2-laser stimulator …