Analysis of familial and sporadic restless legs syndrome in age of onset, gender, and severity features

M Hanson, M Honour, A Singleton, A Crawley… - Journal of …, 2004 - Springer
Abstract Restless Legs Syndrome is characterized by the irresistible, often indescribable
unpleasant urge to move the limbs while resting. It has an estimated prevalence of~ 29.3 …

Epidemiology of restless legs syndrome: a synthesis of the literature

MM Ohayon, R O'Hara, MV Vitiello - Sleep medicine reviews, 2012 - Elsevier
Restless legs syndrome (RLS) has gained considerable attention in the recent years: nearly
50 community-based studies have been published in the last decade around the world. The …

Rheumatologic serologies in secondary restless legs syndrome

W Ondo, EK Tan, J Mansoor - Movement disorders: official …, 2000 - Wiley Online Library
Diagnostic criteria for restless legs syndrome (RLS) have been established; however, the
pathophysiology of this common condition remains elusive. Several secondary forms of RLS …

Restless legs syndrome in Parkinson's disease and other neurodegenerative diseases of the central nervous system

A Iranzo, CL Comella, J Santamaria… - … : official journal of the …, 2007 - Wiley Online Library
The pathophysiology of restless legs syndrome (RLS) is associated with central
dopaminergic system dysfunction leading to speculations that RLS may be common in those …

Achievements, challenges, and future perspectives of epidemiologic research in restless legs syndrome (RLS)

DL Picchietti, SK Van Den Eeden, Y Inoue, K Berger - Sleep medicine, 2017 - Elsevier
In the 20 years since the initial consensus on a common definition for restless legs
syndrome (RLS), over 600 scientific reports on epidemiological aspects of RLS have been …

Family‐based association study of the restless legs syndrome loci 2 and 3 in a European population

D Kemlink, O Polo, P Montagna… - … : official journal of the …, 2007 - Wiley Online Library
Three loci for the restless legs syndrome (RLS) on chromosomes 12q, 14q, and 9p (RLS1,
RLS2, and RLS3) have been mapped, but no gene has been identified as yet. RLS1 has …

Recent advances in the diagnosis, genetics and treatment of restless legs syndrome

C Trenkwalder, B Högl, J Winkelmann - Journal of neurology, 2009 - Springer
Abstract Knowledge of restless legs syndrome (RLS) has greatly increased in recent years
due to the many advances that have been made in diagnosis, management and genetics …

Arm restlessness in patients with restless legs syndrome

M Michaud, A Chabli, G Lavigne… - … : official journal of the …, 2000 - Wiley Online Library
Restless legs syndrome (RLS) is a neurologic disorder characterized principally by leg
paresthesia and motor restlessness. Several clinical reports indicated that many patients …

Prevalence of restless legs syndrome: a community-based study from Argentina

GG Persi, JL Etcheverry, C Vecchi, VL Parisi… - Parkinsonism & Related …, 2009 - Elsevier
BACKGROUND AND PURPOSE: The number of restless legs syndrome (RLS) prevalence
studies performed outside Europe and North America remains small. We conducted a …

Exercise and restless legs syndrome: a randomized controlled trial

MMM Aukerman, D Aukerman… - The Journal of the …, 2006 - Am Board Family Med
Background and Objectives: Restless legs syndrome (RLS) is a common, underdiagnosed
neurological movement disorder of undetermined etiology. The primary treatments for …