Two small RNAs, CrcY and CrcZ, act in concert to sequester the Crc global regulator in Pseudomonas putida, modulating catabolite repression

R Moreno, P Fonseca, F Rojo - Molecular microbiology, 2012 - Wiley Online Library
The Crc protein is a translational repressor that recognizes a specific target at some mRNAs,
controlling catabolite repression and co‐ordinating carbon metabolism in pseudomonads. In …

Pseudomonas putida growing at low temperature shows increased levels of CrcZ and CrcY sRNAs, leading to reduced Crc‐dependent catabolite repression

P Fonseca, R Moreno, F Rojo - Environmental microbiology, 2013 - Wiley Online Library
Summary The Crc protein of Pseudomonas inhibits the expression of genes involved in the
transport and assimilation of a number of non‐preferred carbon sources when preferred …

Small RNA as global regulator of carbon catabolite repression in Pseudomonas aeruginosa

E Sonnleitner, L Abdou, D Haas - Proceedings of the …, 2009 - National Acad Sciences
In the metabolically versatile bacterium Pseudomonas aeruginosa, the RNA-binding protein
Crc is involved in catabolite repression of a range of degradative genes, such as amiE …

[HTML][HTML] Novel Targets of the CbrAB/Crc Carbon Catabolite Control System Revealed by Transcript Abundance in Pseudomonas aeruginosa

E Sonnleitner, M Valentini, N Wenner, FZ Haichar… - PloS one, 2012 - journals.plos.org
The opportunistic human pathogen Pseudomonas aeruginosa is able to utilize a wide range
of carbon and nitrogen compounds, allowing it to grow in vastly different environments. The …

Promoter recognition and activation by the global response regulator CbrB in Pseudomonas aeruginosa

L Abdou, HT Chou, D Haas, CD Lu - Journal of bacteriology, 2011 - Am Soc Microbiol
ABSTRACT In Pseudomonas aeruginosa, the CbrA/CbrB two-component system is
instrumental in the maintenance of the carbon-nitrogen balance and for growth on carbon …

Transcriptional activation of the CrcZ and CrcY regulatory RNAs by the CbrB response regulator in Pseudomonas putida

SM García‐Mauriño, I Pérez‐Martínez… - Molecular …, 2013 - Wiley Online Library
The CbrAB two‐component system has been described as a high‐ranked element in the
regulatory hierarchy of P seudomonas putida that controls a variety of metabolic and …

The Pseudomonas putida Crc global regulator is an RNA binding protein that inhibits translation of the AlkS transcriptional regulator

R Moreno, A Ruiz‐Manzano, L Yuste… - Molecular …, 2007 - Wiley Online Library
The Crc protein is a global regulator that controls the hierarchical assimilation of carbon
sources in Pseudomonads by inhibiting expression of several catabolic pathways. Crc does …

RNA mimicry, a decoy for regulatory proteins

S Marzi, P Romby - Molecular microbiology, 2012 - Wiley Online Library
Small non‐coding RNA molecules (sRNA) are key regulators participating in complex
networks, which adapt metabolism in response to environmental changes. In this issue of …

CrcZ and CrcX regulate carbon source utilization in Pseudomonas syringae pathovar tomato strain DC3000

MJ Filiatrault, PV Stodghill, J Wilson, BG Butcher… - RNA biology, 2013 - Taylor & Francis
Small non-coding RNAs (ncRNAs) are important components of many regulatory pathways
in bacteria and play key roles in regulating factors important for virulence. Carbon catabolite …

[HTML][HTML] The Pseudomonas aeruginosa Catabolite Repression Control Protein Crc Is Devoid of RNA Binding Activity

T Milojevic, I Grishkovskaya, E Sonnleitner… - PLoS …, 2013 - journals.plos.org
The Crc protein has been shown to mediate catabolite repression control in Pseudomonas,
leading to a preferential assimilation of carbon sources. It has been suggested that Crc acts …