With a modified, precise 86Rbmethodplasma digoxin concentration was estimated
inpatients with atrialfibrillation. They received successively increasing digoxin dosesuntil …

The criteria which a drug must fulfil before it can be said that it may be worthwhile making
regular plasma concentration measurements of that drug in monitoring therapy are …

Although therapeutic and toxic serum concentrations of digoxin have been established,
there is sparse information permitting correlation of drug level with clinical effect. This study …

Results Of the io8 subjects studied, 54 were men and 54 were women; 22 (20'4%) were
found to have clinical or electrocardiographic evidence of digoxin toxicity. The results are …

The effect of verapamil on the pharmacokinetics of digoxin was studied in 49 patients with
chronic atrial fibrillation. A dose of 240 mg/day of verapamil was given to the patients who …

Methods Patients admitted in emergency to a general medical ward in the Belfast City
Hospital during the period from March I972 to June I973, who were receiving maintenance …

Serum digoxin estimations were done in 98 patients receiving digoxin for heart failure of
varied aetiology. Digoxin toxicity or the lack of it was determined on the basin of established …

Serum, right atrial myocardium and skeletal muscle collected from 32 adult patients
undergoing open heart surgery were analyzed for digoxin by radioimmunoassay …

Plasma digoxin concentrations were measured by radioimmunoassay in 116 patients with
atrial fibrillation on long-term oral treatment with the drug, and in 23 patients with digoxin …

A prospective survey of the incidence of digitalis toxicity and its correlation with plasma
digoxin levels determined by radioimmunoassay has failed to show any difference between …