Simultaneous assessment of urinary and fecal volatile organic compound analysis in de novo pediatric IBD

S el Manouni el Hassani, S Bosch, JPM Lemmen… - Sensors, 2019 - mdpi.com
Endoscopic evaluation is mandatory in establishing the diagnosis of pediatric inflammatory
bowel disease (IBD), but unfortunately carries a high burden on patients. Volatile organic …

Faecal Volatile Organic Compound Analysis in De Novo Paediatric Inflammatory Bowel Disease by Gas Chromatography–Ion Mobility Spectrometry: A Case–Control …

E Vermeer, JZ Jagt, TK Stewart, JA Covington… - Sensors, 2024 - mdpi.com
The gut microbiota and its related metabolites differ between inflammatory bowel disease
(IBD) patients and healthy controls. In this study, we compared faecal volatile organic …

Diagnosing Inflammatory bowel disease using noninvasive applications of volatile organic compounds: A systematic review

AS Bannaga, A Farrugia… - Expert Review of …, 2019 - Taylor & Francis
Introduction: Inflammatory bowel disease (IBD) is a common disease with significant
morbidity. Noninvasive diagnostic techniques are lacking in IBD. Currently, fecal calprotectin …

Faecal volatile organic compounds analysis using field asymmetric ion mobility spectrometry: Non-invasive diagnostics in paediatric inflammatory bowel disease

N Van Gaal, R Lakenman, J Covington… - Journal of breath …, 2017 - iopscience.iop.org
Abstract Background and Objectives: Inflammatory bowel disease (IBD), including Crohn's
disease (CD) and ulcerative colitis (UC), remains challenging to diagnose. Diagnostic work …

Differentiation between pediatric irritable bowel syndrome and inflammatory bowel disease based on fecal scent: proof of principle study

S Bosch, N van Gaal, RP Zuurbier… - Inflammatory Bowel …, 2018 - academic.oup.com
Background The diagnostic work-up of pediatric irritable bowel syndrome (IBS) and
functional abdominal pain–not otherwise specified (FAP-NOS) commonly includes invasive …

Faecal volatile organic compounds differ according to inflammatory bowel disease sub‐type, severity, and response to treatment in paediatric patients

S Belnour, R Slater, K Tharmaratnam… - United European …, 2024 - Wiley Online Library
Background Faecal volatile organic compounds (VOCs) differ with disease sub‐type and
activity in adults with established inflammatory bowel disease (IBD) taking therapy. Objective …

Sniffing out paediatric gastrointestinal diseases: The potential of volatile organic compounds as biomarkers for disease

M Buijck, DJC Berkhout, EFJ de Groot… - Journal of pediatric …, 2016 - journals.lww.com
The diagnostic work-up and follow-up of paediatric functional gastrointestinal disorders and
organic conditions usually includes invasive tests, carrying a high burden on patients. There …

Metabolomic analysis of breath volatile organic compounds reveals unique breathprints in children with inflammatory bowel disease: a pilot study

N Patel, N Alkhouri, K Eng, F Cikach… - Alimentary …, 2014 - Wiley Online Library
Background Breath testing is becoming an important diagnostic method to evaluate many
disease states. In the light of rising healthcare costs, is important to develop a simple non …

Faecal gas analysis by electronic nose as novel, non-invasive method for assessment of active and quiescent paediatric inflammatory bowel disease: Proof of …

TG De Meij, NK De Boer, MA Benninga… - Journal of Crohn's & …, 2014 - europepmc.org
Inflammatory bowel disease (IBD) and its two phenotypes ulcerative colitis (UC) and Crohn's
disease (CD) are essentially assessed by endoscopy, both in initial diagnostic work-up and …

The Diagnostic Utility of Volatile Organic Compounds in Inflammatory Bowel Disease: A Systematic Review and Meta-Analysis

A Krishnamoorthy, S Chandrapalan… - Journal of Crohn's …, 2024 - academic.oup.com
Abstract Background Volatile organic compounds [VOCs] show promise as potential
biomarkers of for ulcerative colitis and Crohn's disease, two chronic, idiopathic …