Objective: Hyperthyroidism has pronounced effects on vascular function and endothelium-
dependent relaxation. The aim of the present study was to identify mechanisms underlying …

Hypothyroidism impairs endothelium-dependent dilatations, while hyperthyroidism
augments the production of endothelial nitric oxide. Thus, experiments were designed to …

Thyroid disease has profound effects on cardiovascular function. Hypo-and hyperthyroidism,
for example, are associated with reduced and increased maximal endothelium-dependent …

AIM: A hypothyroid state frequently accompanies cardiac illnesses but its physiological
significance for the cardiovascular hemodynamics remains largely unknown. Therefore, the …

Hyperthyroidism was induced by subcutaneous injections of l-thyroxine (T4)(500 mg/kg/day)
for 3 days in order to study whether adrenergic and muscarinic receptor-mediated vascular …

BACKGROUND: Abnormal vascular responsiveness to vasoconstrictors may play an
important role in peripheral vascular resistance in hyperthyroidism. The aim of the present …

AIM: The ability of the thyroid hormone to increase cardiac output and to lower systemic
vascular resistance may provide a novel treatment for cardiovascular diseases. Therefore …

The time-dependent effects of mild hypothyroidism on endothelial function were assessed in
rat mesenteric arteries. Male Wistar rats were treated with methimazole (MMI; 0.003%) or …

Background—Although thyroid hormone (TH) exerts relevant effects on the cardiovascular
system, it is unknown whether TH also regulates vascular reactivity in humans. Methods and …

We investigated the time dependency of hypothyroid-induced changes in β-adrenoceptor-
mediated relaxation of vascular smooth muscle. Methimazole (0.03%) was administered to …