Effect of adiponectin and ghrelin on apoptosis of Barrett adenocarcinoma cell line

PC Konturek, G Burnat, T Rau, EG Hahn… - Digestive diseases and …, 2008 - Springer
Background Obesity is an important risk factor for Barrett adenocarcinoma. However, the
role of adiponectin (anti-inflammatory adipokine from adipose tissue) and ghrelin …

Adiponectin modulates DCA-induced inflammation via the ROS/NF-kappa B signaling pathway in esophageal adenocarcinoma cells

R Zhang, X Yin, H Shi, J Wu, P Shakya, D Liu… - Digestive diseases and …, 2014 - Springer
Background Deoxycholic acid (DCA) promotes the development and progression of
esophageal adenocarcinoma (EAC) by inducing inflammation. Adiponectin is reported to …

Globular adiponectin, acting via adiponectin receptor-1, inhibits leptin-stimulated oesophageal adenocarcinoma cell proliferation

OO Ogunwobi, ILP Beales - Molecular and cellular endocrinology, 2008 - Elsevier
Obesity increases the risk of developing several cancers including oesophageal
adenocarcinoma (OAC). Obesity is characterised by hyperleptinaemia and …

Adiponectin receptor-1 expression is associated with good prognosis in gastric cancer

T Tsukada, S Fushida, S Harada, S Terai… - Journal of Experimental …, 2011 - Springer
Background Adiponectin is inversely related to BMI, positively correlates with insulin
sensitivity, and has anti-atherogenic effects. In recent years, adiponectin has been well …

The role of obesity in oesophageal cancer development

E Long, ILP Beales - Therapeutic advances in …, 2014 - journals.sagepub.com
The incidence of oesophageal adenocarcinoma has increased dramatically in the
developed world in the last half century. Over approximately the same period there has been …

Adiponectin modulates C-jun N-terminal kinase and mammalian target of rapamycin and inhibits hepatocellular carcinoma

NK Saxena, PP Fu, A Nagalingam, J Wang, J Handy… - Gastroenterology, 2010 - Elsevier
BACKGROUND & AIMS: Epidemiological studies have shown that obesity is a risk factor for
hepatocellular carcinoma (HCC). Lower adiponectin levels are associated with poor …

Adipocytokine levels in gastric cancer patients: resistin and visfatin as biomarkers of gastric cancer

TE Nakajima, Y Yamada, T Hamano, K Furuta… - Journal of …, 2009 - Springer
Purpose Adipocytokines are adipocyte-secreted hormones associated with some
malignancies. We investigated the association of adipocytokines with gastric cancer …

Plasma adiponectin and gastric cancer

M Ishikawa, J Kitayama, S Kazama, T Hiramatsu… - Clinical Cancer …, 2005 - AACR
Background: Recently, increased body weight has been associated with an increased risk of
cancers at multiple specific sites, including gastric cancer. Adiponectin is a peptide hormone …

Associations between leptin and adiponectin receptor upregulation, visceral obesity and tumour stage in oesophageal and junctional adenocarcinoma

JM Howard, P Beddy, D Ennis, M Keogan… - Journal of British …, 2010 - academic.oup.com
Background Obesity is associated with oesophageal adenocarcinoma, but mechanisms
linking fat and carcinogenesis remain poorly understood. Altered circulating adipocytokines …

Adiponectin supports cell survival in glucose deprivation through enhancement of autophagic response in colorectal cancer cells

BS Habeeb, J Kitayama, H Nagawa - Cancer science, 2011 - Wiley Online Library
Adiponectin is known to have suppressive effects on tumor growth and is thought to be a key
molecule in the positive correlation between obesity and cancer. However, the detailed …