Atherosclerosis is characterized by the progressive accumulation of lipids and leukocytes in
the arterial wall. Leukocytes such as macrophages accumulate oxidized lipoproteins in the …

Atherosclerosis causing heart attack and stroke is the leading cause of death in the modern
world. Therapy for end-stage atherosclerotic disease using CD34+ hematopoietic cells has …

Atherosclerotic cardiovascular disease is a chronic inflammatory disease of the blood
vessels that can lead to myocardial infarction or stroke. The major cell in the atherosclerotic …

Murphy and Tall Local Macrophage Proliferation in Atherosclerosis 237 not continue
indefinitely and that the macrophage pool of established lesions is ultimately derived from a …

Monocytosis and neutrophilia are frequent events in atherosclerosis. These phenomena
arise from the increased proliferation of hematopoietic stem and multipotential progenitor …

Hematopoiesis is the process that leads to multiple leukocyte lineage generation within the
bone marrow. This process is maintained through-out life thanks to a nonstochastic division …

As the pathological basis of cardiovascular disease (CVD), atherosclerosis is featured as a
chronic inflammation. Hypercholesterolemia is an independent risk factor for CVD …

A central feature of atherosclerosis, the most prevalent chronic vascular disease and root
cause of myocardial infarction and stroke, is leukocyte accumulation in the arterial wall …

Modulation of hematopoietic stem and progenitor cells (HSPCs) determines immune cell
function. In this study, we investigated how hypercholesterolemia affects HSPC biology and …

Impaired regulation of cholesterol metabolism increases the proliferation of hematopoietic
stem and progenitor cells in both the bone marrow and the spleen. Recent findings identified …