A novel and injectable strontium-containing hydroxyapatite bone cement for bone substitution: A systematic evaluation

J Dai, Y Fu, D Chen, Z Sun - Materials Science and Engineering: C, 2021 - Elsevier
Reconstruction of bone defects is still a challenge. In this study, we developed and
systematically evaluated a novel injectable strontium-containing hydroxyapatite (Sr-HA) …

The effect of strontium incorporation into hydroxyapatites on their physical and biological properties

GX Ni, B Shu, G Huang, WW Lu… - Journal of Biomedical …, 2012 - Wiley Online Library
In this study, the effects of a series of strontium (Sr)‐substituted HA ceramics (0, 1, 5, and 10
mol% Sr substitution) were tested on their physical and biological properties. The crystal …

Murine osteoblastic and osteoclastic differentiation on strontium releasing hydroxyapatite forming cements

SS Singh, A Roy, B Lee, S Parekh, PN Kumta - Materials Science and …, 2016 - Elsevier
Ionic substitutions in hydroxyapatite (HA) scaffolds and self-setting cements containing Sr 2+
ions incorporated are particularly of interest in bone regeneration. To date, the approach …

Strontium-substituted calcium sulfate hemihydrate/hydroxyapatite scaffold enhances bone regeneration by recruiting bone mesenchymal stromal cells

H Chang, H Xiang, Z Yao, S Yang… - Journal of …, 2020 - journals.sagepub.com
Fabrication of osteoconductive scaffold with osteoinductive capability and appropriate
resorption rate is of great significance for treating bone defects. To achieve this aim …

[HTML][HTML] A novel fast-setting strontium-containing hydroxyapatite bone cement with a simple binary powder system

L Sun, T Li, S Yu, M Mao, D Guo - Frontiers in Bioengineering and …, 2021 - frontiersin.org
In recent years, strontium-substituted calcium phosphate bone cement (Sr-CPC) has
attracted more and more attentions in the field of bone tissue repair due to its …

An effective approach by a chelate reaction in optimizing the setting process of strontium‐incorporated calcium phosphate bone cement

GM Kuang, WP Yau, WM Lam, J Wu… - … Research Part B …, 2012 - Wiley Online Library
Strontium (Sr) plays a special role in enhancing the biological osteo‐stimulation of calcium
phosphate cement (CPC), not only increasing osteoblast‐related gene expression and the …

Strontium-containing hydroxyapatite bioactive bone cement in revision hip arthroplasty

GX Ni, KY Chiu, WW Lu, Y Wang, YG Zhang, LB Hao… - Biomaterials, 2006 - Elsevier
Clinical outcome of cemented implants to revision total hip replacement (THR) is not as
satisfactory as primary THR, due to the loss of bone stock and normal trabecular pattern …

A novel strontium (II)-modified calcium phosphate bone cement stimulates human-bone-marrow-derived mesenchymal stem cell proliferation and osteogenic …

M Schumacher, A Lode, A Helth, M Gelinsky - Acta biomaterialia, 2013 - Elsevier
In the present study, the in vitro effects of novel strontium-modified calcium phosphate bone
cements (SrCPCs), prepared using two different approaches on human-bone-marrow …

Novel injectable strontium-hardystonite phosphate cement for cancellous bone filling applications

YJ No, X Xin, Y Ramaswamy, Y Li… - Materials Science and …, 2019 - Elsevier
Injectable bone cement (IBC) such as those based on methacrylates and hydraulic calcium
phosphate and calcium sulfate-based cements have been used extensively for filling bone …

[HTML][HTML] In vitro and in vivo evaluation of injectable strontium-modified calcium phosphate cement for bone defect repair in rats

H Xu, L Zhu, F Tian, C Wang, W Wu, B Lu… - International Journal of …, 2022 - mdpi.com
Calcium phosphate cement (CPC) has been widely studied, but its lack of osteoinductivity
and inadequate mechanical properties limit its application, while strontium is able to …