Isolation and analysis of tumor cell subpopulations using biomimetic immuno‐fluorescent magnetic multifunctional nanoprobes

Q Li, Z Liao, L Han, L Li, Y Song… - Advanced Functional …, 2020 - Wiley Online Library
Tumor cell heterogeneity leads to differences in tumor proliferation and invasiveness, as
well as drug sensitivity. These factors affect the diagnosis, treatment, and monitoring of …

Gradient Magnetic Separation and Fluorescent Imaging‐Based Heterogeneous Circulating Tumor Cell Subpopulations Assay with Biomimetic Multifunctional …

Z Liao, L Han, Q Li, L Li, Y Liu, Y Song… - Advanced Functional …, 2021 - Wiley Online Library
The heterogeneity of circulating tumor cells (CTCs) greatly impacts cancer metastasis and
malignancy, contributing to increased mortality. Therefore, the analysis of such …

Engineering magnetic nanoparticles and their integration with microfluidics for cell isolation

M Unni, J Zhang, TJ George, MS Segal, ZH Fan… - Journal of colloid and …, 2020 - Elsevier
Isolation of cancer cells, bacteria, and viruses from peripheral blood has important
applications in cancer diagnosis, therapy monitoring, and drug development. Magnetic …

Towards ideal magnetofluorescent nanoparticles for bimodal detection of breast‐cancer cells

F Corsi, C De Palma, M Colombo, R Allevi, M Nebuloni… - Small, 2009 - Wiley Online Library
An increasing number of novel molecular markers based on nanomaterials for tumor
diagnostics have been developed in recent years. Many efforts have focused on the …

Multi-shell structured fluorescent–magnetic nanoprobe for target cell imaging and on-chip sorting

PH Zhang, JT Cao, QH Min, JJ Zhu - ACS Applied Materials & …, 2013 - ACS Publications
In this paper, we have developed a core-triple-shell structured multi-functional nanoprobe
Fe3O4/SiO2/CdSeTe@ ZnS–SiO2/polydopamine with strong fluorescence and a fast …

Efficient targeted cancer cell detection, isolation and enumeration using immuno-nano/hybrid magnetic microgels

A Seyfoori, SAS Ebrahimi, A Yousefi, M Akbari - Biomaterials science, 2019 - pubs.rsc.org
Magnetic nanomaterials have drawn ample attention in the field of biotechnology due to
their excellent magnetic properties and biocompatibility. These materials have been widely …

Micromagnetic cancer cell immobilization and release for real-time single cell analysis

D Jaiswal, AT Rad, MP Nieh, KP Claffey… - Journal of Magnetism …, 2017 - Elsevier
Understanding the interaction of live cells with macromolecules is crucial for designing
efficient therapies. Considering the functional heterogeneity found in cancer cells, real-time …

Visual recognition and efficient isolation of apoptotic cells with fluorescent-magnetic-biotargeting multifunctional nanospheres

EQ Song, GP Wang, HY Xie, ZL Zhang, J Hu… - Clinical …, 2007 - academic.oup.com
Background: Fluorescent-magnetic-biotargeting multifunctional nanospheres are likely to
find important applications in bioanalysis, biomedicine, and clinical diagnosis. We have …

Fluorescent-magnetic-biotargeting multifunctional nanobioprobes for detecting and isolating multiple types of tumor cells

EQ Song, J Hu, CY Wen, ZQ Tian, X Yu, ZL Zhang… - ACS …, 2011 - ACS Publications
Fluorescent-magnetic-biotargeting multifunctional nanobioprobes (FMBMNs) have attracted
great attention in recent years due to their increasing, important applications in biomedical …

Characterization of Microscopic Structures in Living Tumor by In Vivo Measurement of Magnetic Relaxation Time Distribution of Intratumor Magnetic Nanoparticles

S Ota, H Kosaka, K Honda, K Hoshino… - Advanced …, 2024 - Wiley Online Library
Tumor microscopic structure is crucial for determining properties such as cancer type,
disease state (key for early diagnosis), and novel therapeutic strategies. Magnetic particle …