To extend our ongoing characterization of modulatory influences on hepatic tumorigenesis,
we examined effects of rat strain (Sprague-Dawley versus Fischer), diet composition …

The effect of varying the amount and type of dietary fat on the promotion of γ-
glutamyltranspeptidase (GGT)-positive foci and hepatocarcinomas in female rats was …

Using the procedure of Solt and Farber for the rapid induction of foci of altered hepatocytes,
we investigated the effect of a choline-devoid (CD) diet on the emergence of such foci in the …

The incidence of gamma-glutamyltranspeptidase (GGT)-positive foci induced by 0.3
mmol/kg diethylnitrosamine (DENA) followed by promotion with 500 ppm sodium …

Butylated hydroxytoluene (BHT) at concentrations of 300–600 ppm in the diet caused a dose-
dependent increase in γ-glutamyl transpeptidase (GGT) activity in normal F344 male rat liver …

Gamma Glutamyltranspeptidase (GGTase)-positive foci have been used to indicate activity
in an initiation/promotion bioassay in rat liver. This rat liver foci bioassay has been proposed …

The ingestion of an elevated level (2%) of l-tryptophan (TRP) in a purified diet was
investigated to determine whether it would influence the induction of γ …

A series of experiments was performed to investigate whether, after exposure of rats to a
chemical hepatocarcinogen, feeding a choline-deficient (CD) diet would promote the …

Although expression of the enzyme gamma-glutamyl transpeptidase (GGT) is the most
common phenotypic marker of preneoplastic foci in the livers of carcinogen-treated rats, it is …

The effect of feeding phenobarbital (PHB) with a cholinedevoid (CD) diet on the emergence
of foci of γ-glutamyltranspeptidase (GGT)-positive hepatocytes in the liver of carcinogen …