Osteomyelitis carries a high risk of recurrence even after extended, aggressive antibiotic
therapy. One of the key challenges is to eradicate the reservoirs of methicillin-resistant …

Bacterial biofilms are major causes of persistent and recurrent infections and implant
failures. Biofilms are formable by most clinically important pathogens worldwide, such as …

Conventional antibiotic treatment is in most cases insufficient to eradicate biofilm-related
infections, resulting in high risk of treatment failure and recurrent infections. Recent studies …

The clinical applications of nanotechnology are emerging as widely popular, particularly as
a potential treatment approach for infectious diseases. Diseases associated with multiple …

Infected wound healing remains a challenging task in clinical practice due to several
factors:(I) drug-resistant infections caused by various pathogens,(II) persistent inflammation …

The increasing incidence of microbial infections and a limited arsenal of effective
antibacterial and antifungal agents have entailed the need for new broad-spectrum …

Staphylococcus aureus (S. aureus) is a leading human pathogen capable of producing
severe invasive infections such as bacteremia, sepsis, and endocarditis with high morbidity …

Intracellular pathogenic bacteria use immune cells as hosts for bacterial replication and
reinfection, leading to challenging systemic infections including peritonitis. The spread of …

Methicillin-resistant Staphylococcus aureus (MRSA) infections pose a serious threat
worldwide. MRSA is the predominant species isolated from medical-device-related biofilm …

Bacterial resistance to antimicrobial compounds is a growing concern in medical and public
health circles. Overcoming the adaptable and duplicative resistance mechanisms of bacteria …