Studies using selective agonists have suggested that the contractile effect of extracellular
nucleotides, such as ATP and UTP, in blood vessels is mediated mainly by P2X1receptors …

It has previously been shown that ATP and UTP stimulate P2Y receptors in vascular smooth
muscle cells (VSMCs), but the nature of these receptors, in particular the contribution of …

Previous studies have shown that ATP and UTP are able to stimulate phospholipase C
(PLC) and proliferation in cultured aortic smooth muscle cells. Here we set out to …

The ATP-and UTP-sensitive P2Y2receptor which mediates both contractile and mitogenic
effects has recently been shown to be upregulated in the synthetic phenotype of the vascular …

The expression of mRNAs for three P2X receptor subtypes (PX2 1, P2X 2, P2X 4) in the rat
vascular system was studied by in situ hybridization and RT-PCR. In heart sections mRNAs …

Background and purpose: The uracil nucleotides UDP and UTP have been reported to
activate P2Y2, P2Y4 and P2Y6 receptors to cause vasoconstriction. We have performed a …

P2 receptors mediate the actions of the extracellular nucleotides ATP, ADP, UTP, and UDP,
regulating several physiologic responses including cardiac function, vascular tone, smooth …

Nucleotides regulate various effects including vascular tone. This study was aimed to
characterize P2Y receptors on endothelial cells of the aorta of C57BL6 mice. Five adjacent …

Extracellular nucleotides were used to characterise the contractile P2 receptors in the rat
basilar artery. The isometric tension was recorded in vitro and receptor mRNA expression …

The actions of ATP and uridine 5′-triphosphate (UTP) were compared at P2X1 receptors in
acutely dissociated smooth muscles cells of the rat tail artery. ATP (30 nM–100 μM) and UTP …