Development and Characterization of an Antimicrotubular Taxane Loaded MPEG‐b‐PCL Nanoparticles

V Rajasekharreddy - 2012 - repository-tnmgrmu.ac.in
The present work entitled,“Development and characterisation of an Antimicrotubular Taxane
loaded MPEG-b-PCL Nanoparticles” was aimed to develop a nanoparticulate drug delivery …

Development of high drug loaded and customizing novel nanoparticles for modulated and controlled release of paclitaxel

PP Di Mauro, S Borrós - Pharmaceutical research, 2014 - Springer
Purpose The objective of this study was to develop a custom-tailored polymeric drug
delivery system for paclitaxel, employing a novel biodegradable block co-polymer (P) …

HA-PEG-PCL Nanoparticles for Targeted Delivery of Paclitaxel to Colon Cancer

D Jain, D Chumbhale - NeuroQuantology, 2022 - search.proquest.com
For improved treatment efficacy with no or few adverse effects and higher patient
compliance, novel delivery techniques with selective dispersion are required. The …

[PDF][PDF] Development of a novel nanoparticulate form of paclitaxel for cancer treatment

Y Khamdi - tntconf.org
Paclitaxel (Ptx) is a taxane anticancer mitotic inhibitor, widely used in oncology for the last
20 years. Poor solubility of Ptx, as a consequence using of toxic solvents such as Cremofor …

Development of methoxy poly (ethylene glycol)-block-poly (caprolactone) amphiphilic diblock copolymer nanoparticulate formulations for the delivery of paclitaxel

KJ Letchford - 2008 - open.library.ubc.ca
The goal of this project was to develop a non-toxic amphiphilic diblock copolymer
nanoparticulate drug delivery system that will solubilize paclitaxel (PTX) and retain the drug …

Formulation and evaluation of protein bound paclitaxel nanoparticles for injectable suspension

SK Jain, S Thakur, R Jain, N Jain - Journal of Drug Delivery and …, 2020 - jddtonline.info
Aims: The aim of present study is to develop Paclitaxel nanoparticles for injectable
suspension, an anti-neoplastic drug formulation. Study design: Mention the design of the …

Characterization, pharmacokinetics and disposition of novel nanoscale preparations of paclitaxel

C Wang, YJ Wang, YJ Wang, M Fan, F Luo… - International journal of …, 2011 - Elsevier
Polymeric nanoparticles (NPs) have great potential application in achieving targeted
delivery of anticancer drugs. Paclitaxel (PTX) loaded NPs were developed using …

In vitro human plasma distribution of nanoparticulate paclitaxel is dependent on the physicochemical properties of poly (ethylene glycol)-block-poly (caprolactone) …

K Letchford, R Liggins, KM Wasan, H Burt - European journal of …, 2009 - Elsevier
In this study, we synthesized and characterized two methoxy poly (ethylene glycol)-block-
poly (caprolactone)(MePEG-b-PCL) amphiphilic diblock copolymers, both based on MePEG …

Paclitaxel-loaded TPGS-b-PCL nanoparticles: in vitro cytotoxicity and cellular uptake in MCF-7 and MDA-MB-231 cells versus mPEG-b-PCL nanoparticles and …

E Bernabeu, L Gonzalez, MJ Legaspi… - … of nanoscience and …, 2016 - ingentaconnect.com
Nanomedicines have become an attractive platform for the development of novel drug
delivery systems in cancer chemotherapy. Polymeric nanoparticles (NPs) represent one of …

Characterization and in-vitro bioactivity evaluation of paclitaxel-loaded polyester nanoparticles

P Lopez-Gasco, I Iglesias, J Benedi, R Lozano… - Anti-Cancer …, 2012 - journals.lww.com
Paclitaxel, an antimicrotubular agent used in the treatment of ovarian and breast cancer,
was encapsulated in nanoparticles of poly (DL-lactide-co-glycolide) and poly (ε …