UK real-world experience of prescribing rivaroxaban for acute venous thromboembolism in obesity: results from the FIRST registry

V Speed, JP Patel, LN Roberts… - Thrombosis …, 2021 - thrombosisresearch.com
1. Background The treatment of acute venous thromboembolism (VTE) in patients with
bodyweight> 120 kg or BMI> 40 kg/m 2 with a direct oral anticoagulant (DOAC) is …

Comparing the efficacy and safety of direct oral anticoagulants with warfarin in the morbidly obese population with atrial fibrillation

K Kido, S Ngorsuraches - Annals of Pharmacotherapy, 2019 - journals.sagepub.com
Background: The International Society of Thrombosis and Haemostasis recommends
avoiding direct oral anticoagulants (DOACs) in morbidly obese patients with a body mass …

[HTML][HTML] Peak plasma concentration of direct oral anticoagulants in obese patients weighing over 120 kilograms: a retrospective study

S Piran, H Traquair, N Chan, V Bhagirath… - Research and practice …, 2018 - Elsevier
Background Due to a paucity of data on the efficacy and safety of direct oral anticoagulants
(DOACs) in patients with a body mass index> 40 kg/m 2 or a weight> 120 kg, the use of …

Treatment of Atrial Fibrillation and Venous Thromboembolism with Factor Xa Inhibitors in Severely Obese Patients

P Dobry, SB Edwin, B Haymart, GD Barnes… - Journal of Thrombosis …, 2024 - Elsevier
Background A paucity of data exists to support the use of factor Xa inhibitors in severely
obese patients with a weight≥ 150kg or BMI≥ 50 kg/m 2. Objectives The purpose of this …

Impact of BMI on clinical outcomes of NOAC therapy in daily care-Results of the prospective Dresden NOAC Registry (NCT01588119)

L Tittl, S Endig, S Marten, A Reitter… - International journal of …, 2018 - Elsevier
Direct acting non-Vitamin K antagonist oral anticoagulants (NOAC) are characterized by a
fixed dosing regimen. Despite the potential for relative underdosing due to large distribution …

Management of venous thromboembolism in morbidly obese patients: A 10-year review

B Wee, B Lui, J Lai, Z Khattak, A Kwok… - Journal of Thrombosis …, 2023 - Springer
Obesity is a known risk factor for venous thromboembolism (VTE) and poses a unique set of
challenges in anticoagulation management. We report a 10-year experience of VTE …

Comparative effectiveness and safety of direct oral anticoagulants in obese patients with atrial fibrillation

A Briasoulis, A Mentias, A Mazur, P Alvarez… - … drugs and therapy, 2021 - Springer
Background Unlike warfarin direct oral anticoagulants (DOACs) are administered in fixed
doses, which raises concerns of its effectiveness on larger patients. Data from randomized …

Effect of body weight on efficacy and safety of direct oral anticoagulants in the treatment of patients with acute venous thromboembolism: a meta-analysis of …

MND Di Minno, R Lupoli, A Di Minno… - Annals of …, 2015 - Taylor & Francis
Objective. To evaluate the effect of body weight (BW) on safety and efficacy of direct oral
anticoagulants (DOACs). Methods. We performed a meta-analysis of randomized controlled …

Direct oral anticoagulants in patients with obesity and atrial fibrillation: position paper of Italian National Association of Hospital Cardiologists (ANMCO)

D Mocini, SA Di Fusco, E Mocini, LM Donini… - Journal of Clinical …, 2021 - mdpi.com
The use of the direct oral anticoagulants dabigatran, rivaroxaban, apixaban and edoxaban
(DOACs) offers some major advantages over warfarin and other vitamin K antagonists …

Effectiveness and safety of non-vitamin K antagonist oral anticoagulant in the treatment of patients with morbid obesity or high body weight with venous …

H Zhang, H Xie, X Wang, Z Zhu, F Duan - Medicine, 2023 - journals.lww.com
Background: Venous thromboembolism (VTE) poses a significant health risk to patients with
morbid obesity or high body weight. Non-vitamin K antagonist oral anticoagulants (NOACs) …