OBJECTIVES Constipation is common, and its treatment is unsatisfactory. Although many
agents have been tried, there are limited data to support their use. Our aim was to undertake …

Chronic constipation is a common functional gastrointestinal disorder that affects patients of
all ages. In 2007, a consensus group of 10 Canadian gastroenterologists developed a set of …

METHODS: We searched PubMed and Embase for randomized controlled trials of≥ 4-week
duration that evaluated OTC preparations between 2004 and 2020. Studies were scored …

BACKGROUND: Constipation is an uncomfortable and common condition that affects many,
irrespective of age. Since 1500 BC and before, health care practitioners have provided …

Constipation is a common gastrointestinal motility disorder that is often chronic, negatively
affects patients' daily lives, and is associated with high healthcare costs. There is a …

Introduction Chronic idiopathic constipation (CIC) is a common disorder associated with
significant impairment in quality of life. This clinical practice guideline, jointly developed by …

This document presents the official recommendations of the American Gastroenterological
Association (AGA) on constipation. It was drafted by the AGA Institute Medical Position …

Chronic constipation (CC) is characterized by unsatisfactory defecation that results from
infrequent stools, difficult stool passage, or both. The pathophysiology of CC is multifactorial …

Background There are several drugs available for the treatment of chronic idiopathic
constipation, but their relative efficacy is unclear because there have been no head-to-head …

In order to fulfill these requirements, Task Force members followed the techniques used to
produce a previous American College of Gastroenterology evidence-based monograph (4) …