Early clinical studies revealed that timolol and other topical β blockers were effective in
reducing intra‐ocular pressure, without the side effects associated with other antiglaucoma …

Glaucoma, a disease that affects between 1 and 3% of the population above the age of 60,
is most commonly treated by topical beta‐adrenergic blockers. Although effective in lowering …

Early clinical studies reported that timolol and other topical beta-blockers were effective in
reducing intraocular pressure, without the side effects associated with other antiglaucoma …

Although topical [beta]-blockers are generally tolerated, they can produce significant
systemic side effects. The systemic side effects of nonselective [beta]-blockers (eg, timolol …

In the twenty years since beta-blockers were proposed for treatment of glaucoma, use of
topical timolol has increased to account for 70% of all glaucoma medications used. The …

Topical β-blockers reduce the intraocular pressure (IOP) by blockade of sympathetic nerve
endings in the ciliary epithelium causing a fall in aqueous humour production. Two types of …

Since the late 1970s, topical β‐adrenergic blockers have been the drugs of choice in
treating ocular hypertension and associated glaucoma. The currently available drugs are …

Glaucoma and ocular hypertension are highly prevalent conditions in individuals over the
age of 40 and are commonly seen together in patients with cardiovascular disease. Many of …

Topically administered beta blockers are the preferred medical therapy for glaucoma. These
agents reduce intraocular pressure (IOP), thereby preventing damage to the optic nerve and …

The pharmacologic differences between the betablockers currently used for pressure
reduction in patients suffering from glaucoma have become of more than academic interest …