Reduced neural connectivity but increased task‐related activity during working memory in de novo P arkinson patients
JP Trujillo, NJHM Gerrits, DJ Veltman… - Human brain …, 2015 - Wiley Online Library
Abstract Objective: Patients with Parkinson's disease (PD) often suffer from impairments in
executive functions, such as working memory deficits. It is widely held that dopamine …
executive functions, such as working memory deficits. It is widely held that dopamine …
[HTML][HTML] Brain functional connectivity in de novo Parkinson's disease patients based on clinical EEG
M Conti, R Bovenzi, E Garasto, T Schirinzi… - Frontiers in …, 2022 - frontiersin.org
In Parkinson's disease (PD), cortical–subcortical interplay plays a relevant role in affecting
clinical performance. Functional MRI sequences described changes in functional …
clinical performance. Functional MRI sequences described changes in functional …
Resting state functional connectivity of the subthalamic nucleus in P arkinson's disease assessed using arterial spin‐labeled perfusion f MRI
MA Fernández‐Seara, E Mengual… - Human brain …, 2015 - Wiley Online Library
Neurophysiological changes within the cortico‐basal ganglia‐thalamocortical circuits
appear to be a characteristic of Parkinson's disease (PD) pathophysiology. The subthalamic …
appear to be a characteristic of Parkinson's disease (PD) pathophysiology. The subthalamic …
[HTML][HTML] Enhanced functional connectivity between putamen and supplementary motor area in Parkinson's disease patients
Parkinson's disease (PD) is a surprisingly heterogeneous disorder with symptoms including
resting tremor, bradykinesia and rigidity. PD has been associated with abnormal task related …
resting tremor, bradykinesia and rigidity. PD has been associated with abnormal task related …
Resting state fMRI reveals increased subthalamic nucleus–motor cortex connectivity in Parkinson's disease
S Baudrexel, T Witte, C Seifried, F von Wegner… - Neuroimage, 2011 - Elsevier
Parkinson's disease (PD) is associated with abnormal hypersynchronicity in basal ganglia-
thalamo-cortical loops. The clinical effectiveness of subthalamic nucleus (STN) high …
thalamo-cortical loops. The clinical effectiveness of subthalamic nucleus (STN) high …
Dopamine depletion alters macroscopic network dynamics in Parkinson's disease
Parkinson's disease is primarily characterized by diminished dopaminergic function;
however, the impact of these impairments on large-scale brain dynamics remains unclear. It …
however, the impact of these impairments on large-scale brain dynamics remains unclear. It …
Distinct effects of motor training on resting-state functional networks of the brain in Parkinson's disease
Background. Nigrostriatal dopaminergic loss is a hallmark of Parkinson's disease (PD)
pathophysiology, leading to motor Parkinsonism. Different intervention protocols have …
pathophysiology, leading to motor Parkinsonism. Different intervention protocols have …
[HTML][HTML] Dynamic alterations of spontaneous neural activity in Parkinson's disease: a resting-state fMRI study
C Zhang, B Dou, J Wang, K Xu, H Zhang… - Frontiers in …, 2019 - frontiersin.org
Objective: To investigate the dynamic amplitude of low-frequency fluctuations (dALFFs) in
patients with Parkinson's disease (PD) and healthy controls (HCs) and further explore …
patients with Parkinson's disease (PD) and healthy controls (HCs) and further explore …
Voxel‐wise meta‐analysis of gray matter abnormalities in idiopathic Parkinson's disease
PL Pan, W Song, HF Shang - European journal of neurology, 2012 - Wiley Online Library
Structural neuroimaging studies on idiopathic Parkinson's disease (IPD) with voxel‐based
morphometry (VBM) yielded variable and conflicting findings. A systematic review of VBM …
morphometry (VBM) yielded variable and conflicting findings. A systematic review of VBM …
[HTML][HTML] Distinct alterations in Parkinson's medication-state and disease-state connectivity
Altered brain connectivity has been described in people with Parkinson's disease and in
response to dopaminergic medications. However, it is unclear whether dopaminergic …
response to dopaminergic medications. However, it is unclear whether dopaminergic …