Controversy remains as to the efficacy, route of administration and dose of
glucocorticosteroid (GCS) in multiple sclerosis (MS) therapy. With the recent approval of new …

Glucorticorticoids have both anti-inflammatory and immunosuppressive properties and both
synthetic and natural glucocorticoid medications have been used to treat a number of …

High-dose intravenous glucocorticosteroids (GS) are the treatment of choice for acute
relapses in patients with multiple sclerosis. We review the evidence from published trials on …

Multiple sclerosis (MS) is an inflammatory demyelinating disorder characterized by a
multiphasic course of neurological exacerbations, periods of clinical remission, and, in most …

Corticosteroids (Cs) are widely used for treatment of multiple sclerosis (MS) acute relapses
because of the potent immunosuppressive and anti-inflammatory properties. As for patients …

Objectives Relapse management is a crucial component of multiple sclerosis (MS) care.
High-dose corticosteroids (CSs) are used to dampen inflammation, which is thought to …

Glucocorticoids exert a variety of immunomodulatory activities. Since changes in
glucocorticoid homeostasis impact on susceptibility to autoimmune diseases, and synthetic …

Corticosteroids (CS) remain a mainstay of treatment for relapses in multiple sclerosis (MS)
and optic neuritis. Currently, there is not enough evidence that long-term corticosteroid …

Background–Multiple sclerosis (MS) is an immune‐mediated inflammatory disease of the
central nervous system (CNS) that usually is clinically characterized by repeated subacute …

Endogenous glucocorticoids (GC), which are under control of the hypothalamic-pituitary-
adrenal axis, play an important role in controlling chronic inflammatory demyelinating …