Pain and opioid use in chronic liver disease

SS Rogal, D Winger, K Bielefeldt, E Szigethy - Digestive diseases and …, 2013 - Springer
Background Pain is common in patients with liver disease, difficult to treat, and poorly
understood. Aims The aim of this study was to determine factors associated with pain and …

Healthcare utilization in chronic liver disease: the importance of pain and prescription opioid use

SS Rogal, D Winger, K Bielefeldt, BL Rollman… - Liver …, 2013 - Wiley Online Library
Abstract Background & Aims The aim of this study was to assess factors associated with
healthcare utilization in patients with chronic liver disease with a focus on pain, opioid use …

[PDF][PDF] Patterns of inpatient opioid use and related adverse events among patients with cirrhosis: A propensity‐matched analysis

JB Rubin, JC Lai, AM Shui… - Hepatology …, 2021 - Wiley Online Library
Pain is common among patients with cirrhosis, yet managing pain in this population is
challenging. Opioid analgesics are thought to be particularly high risk in patients with …

Inflammation, psychiatric symptoms, and opioid use are associated with pain and disability in patients with cirrhosis

SS Rogal, K Bielefeldt, AD Wasan, FE Lotrich… - Clinical …, 2015 - Elsevier
Background & Aims Cirrhosis is associated with significant pain and disability, the etiologies
of which are poorly understood. We investigated whether the pain and disability in patients …

The assessment and management of pain in cirrhosis

M Klinge, T Coppler, JM Liebschutz, M Dugum… - Current hepatology …, 2018 - Springer
Abstract Purpose of Review The treatment of pain in patients with cirrhosis is complicated by
unpredictable hepatic drug metabolism and a higher risk of adverse drug reactions. We …

[HTML][HTML] Opioid drugs in patients with liver disease: a systematic review

H Soleimanpour, S Safari, KS Nia, S Sanaie… - Hepatitis …, 2016 - ncbi.nlm.nih.gov
Results In patients with liver disease, administration of opioid analgesics should be
observed, accurately. As a general rule, lower doses of drugs should be administered at …

[HTML][HTML] The therapeutic use of analgesics in patients with liver cirrhosis: a literature review and evidence-based recommendations

F Imani, M Motavaf, S Safari, SM Alavian - Hepatitis monthly, 2014 - ncbi.nlm.nih.gov
Results: Paracetamol is safe in patients with chronic liver disease but a reduced dose of 2-3
g/d is recommended for long-term use. Non-steroidal anti-inflammatory drugs (NSAIDs) are …

Opioid prescriptions are associated with hepatic encephalopathy in a national cohort of patients with compensated cirrhosis

AM Moon, Y Jiang, SS Rogal, EB Tapper… - Alimentary …, 2020 - Wiley Online Library
Background Opioids are often prescribed for pain in cirrhosis and may increase the risk of
hepatic encephalopathy (HE). Aim To assess the association between opioids and HE in …

Chronic pain among liver transplant candidates

A Madan, KS Barth, WE Balliet… - Progress in …, 2012 - journals.sagepub.com
Context Little systematic research has been conducted to understand pain among persons
with end-stage liver disease, especially among liver transplant candidates. Appropriate pain …

Characteristics of opioid prescriptions to veterans with cirrhosis

SS Rogal, LA Beste, A Youk, MJ Fine, B Ketterer… - Clinical …, 2019 - Elsevier
Background & Aims Despite increased risks for adverse effects in patients with cirrhosis, little
is known about opioid prescriptions for this population. We aimed to assess time trends in …