Background COMISA is a common disorder that results in nighttime awakenings, daytime
sleepiness and PAP intolerance. Cognitive behavioral therapy for insomnia is used to …

Methods Among 87 patients who were prescribed PRM at the sleep clinic, 44 patients with
primary insomnia who complained of poor sleep quality even after adopting a set 7-hour …

Objectives A multitude of physical and mental challenges are being faced in the population
with Co-morbid Insomnia and Sleep Apnea (COMISA). Unfortunately, research about clinical …

Introduction Obstructive sleep apnea (OSA) can lead to numerous adverse health sequelae,
increased medical costs and impaired quality of life, and insomnia may have similar …

Abstract Purpose of Review Insomnia and sleep apnoea are the two most prevalent sleep
disorders and frequently co-exist. Co-morbid insomnia and sleep apnoea (COMISA) is …

Introduction: Immediate release (IR) melatonin formulations help promote sleep onset, but
poor gastrointestinal absorption prevents them from providing adequate sleep maintenance …

OBJECTIVES We performed a systematic review of randomized controlled trials (RCTs) to
estimate the efficacy of melatonin versus placebo or other hypnotic agents on the …

Objective: Melatonin, the hormone produced nocturnally by the pineal gland, serves as a
circadian time cue and sleep-anticipating signal in humans. With age, melatonin production …

Introduction The purpose of this study was to compare the efficacy of three treatment
sequences using CPAP with or without CBT-I for the treatment of comorbid insomnia and …

We conducted systematic reviews and meta-analyses to evaluate the efficacy of melatonin
versus placebo or other hypnotic agents in improving sleep quality and quantity in patients …