TNFα and IL-10 gene polymorphisms in inflammatory bowel disease. Association of− 1082 AA low producer IL-10 genotype with steroid dependency

P Castro-Santos, A Suarez, L López-Rivas… - Official journal of the …, 2006 - journals.lww.com
OBJECTIVES An altered production of cytokines underlies inflammatory bowel disease
(IBD) susceptibility. Various polymorphisms at the IL-10 and TNFα gene promoters control …

Immune response and gene polymorphism profiles in Crohn's disease and ulcerative colitis

DMM Queiroz, AG Oliveira, IEB Saraiva… - Inflammatory bowel …, 2009 - academic.oup.com
Background Polymorphisms in genes linked to the innate and adaptive immune response
may be involved in inflammatory bowel disease pathogenesis. Our aim was to investigate …

Association between inflammatory bowel disease gene 5 (IBD5) and interleukin‐23 receptor (IL23R) genetic polymorphisms in Malaysian patients with Crohn's …

KH Chua, I Hilmi, LH Lian… - Journal of digestive …, 2012 - Wiley Online Library
OBJECTIVE: This study was aimed to investigate the possible association of Crohn's
disease (CD) with inflammatory bowel disease gene 5 (IBD5) IGR2198a_1 (rs11739135) …

IL4, IL10, IL16, and TNF polymorphisms in New Zealand Caucasian Crohn's disease patients

J Hong, E Leung, AG Fraser, TR Merriman… - International journal of …, 2008 - Springer
Dear Editor: Crohn's disease (CD; OMIM 266600) is a multi-factorial, polygenic disease
characterized by differential production of a number of cytokines that potentially contribute to …

Genetic association of nonsynonymous variants of the IL23R with familial and sporadic inflammatory bowel disease in women

Z Lin, L Poritz, A Franke, TY Li, A Ruether… - Digestive diseases and …, 2010 - Springer
Purpose To replicate the association of IL23R R381Q (rs11209026) with inflammatory bowel
disease (IBD), examine the effect of the two nonsynonymous variations, Q3H and L310P, on …

[HTML][HTML] NOD2, IL23R and ATG16L1 polymorphisms in Lithuanian patients with inflammatory bowel disease

J Sventoraityte, A Zvirbliene, A Franke… - World Journal of …, 2010 - ncbi.nlm.nih.gov
AIM: To investigate the frequency of NOD2, IL23R and ATG16L1 genetic variants in a case-
control panel for inflammatory bowel disease (IBD) from Lithuania. METHODS: One hundred …

Interleukin‐12B gene rs6887695 and rs2288831 polymorphisms are associated with an increased risk of ulcerative colitis development in Chinese Han population: A …

H Zhao, YZ Qian, HH Qian - Journal of Clinical Laboratory …, 2020 - Wiley Online Library
Background The association of the interleukin (IL)‐12B gene rs6887695 and rs2288831
polymorphisms with ulcerative colitis (UC) risk has been extensively investigated, but results …

Ethnic differences in allelic associations of the interleukin-1 gene cluster in South African patients with inflammatory bowel disease (IBD) and in control individuals

O Mwantembe, MC Gaillard, M Barkhuizen, V Pillay… - Immunogenetics, 2001 - Springer
The allelic frequencies of TaqI, PstI, and variable number of tandem repeat (VNTR)
polymorphisms of the IL-1β, IL-1 receptor (IL-1Re), and IL-1 receptor antagonist (IL-1Ra) …

[HTML][HTML] Genetic association and epistatic interaction of the interleukin-10 signaling pathway in pediatric inflammatory bowel disease

Z Lin, Z Wang, JP Hegarty, TR Lin, Y Wang… - World journal of …, 2017 - ncbi.nlm.nih.gov
AIM To study the genetic association and epistatic interaction of the interleukin (IL)-10 and IL-
10/STAT3 pathways in pediatric inflammatory bowel disease (IBD). METHODS A total of 159 …

Heterozygosity for IL23R p.Arg381Gln confers a protective effect not only against Crohn's disease but also ulcerative colitis

C Büning, HHJ SCHMIDT, T Molnar… - Alimentary …, 2007 - Wiley Online Library
Background A recent study reported that a non‐synonymous single nucleotide
polymorphism (rs11209026, p. Arg381Gln) located in the IL23R gene is a protective marker …