[HTML][HTML] The discovery, structure, and function of 5-HTR1E serotonin receptor

VK Sharma, YP Loh - Cell Communication and Signaling, 2023 - Springer
Abstract Serotonin (5-hydroxytryptamine, 5-HT) is a unique neurotransmitter which can
regulate various biological processes by activating thirteen different receptors. These …

[PDF][PDF] Neuronal 5-HT receptors and SERT

NM Barnes, JF Neumaier - Tocris Biosci Sci Rev Ser, 2011 - resources.tocris.com
Introduction 5-hydroxytryptamine (5-HT, serotonin) is an ancient biochemical manipulated
through evolution to be utilized extensively throughout the animal and plant kingdoms …

The serotonin 5-HT7 receptors: two decades of research

E Gellynck, K Heyninck, KW Andressen… - Experimental brain …, 2013 - Springer
Like most neurotransmitters, serotonin possesses a simple structure. However, the
pharmacological consequences are more complex and diverse. Serotonin is involved in …

[HTML][HTML] The serotonin-6 receptor as a novel therapeutic target

HM Yun, H Rhim - Experimental neurobiology, 2011 - ncbi.nlm.nih.gov
Abstract Serotonin (5-hydroxytryptamine, 5-HT) is an important neurotransmitter that is found
in both the central and peripheral nervous systems. 5-HT mediates its diverse physiological …

Characterization of the novel human serotonin receptor subunits 5-HT3C, 5-HT3D, and 5-HT3E

B Niesler, J Walstab, S Combrink, D Moeller… - Molecular …, 2007 - ASPET
Within the family of serotonin receptors, the 5-hydroxytryptamine-3 (5-HT3) receptor is the
only ligand-gated ion channel. It is composed of five subunits, of which the 5-HT3A and 5 …

Development and challenges in the discovery of 5-HT1A and 5-HT7 receptor ligands

D Singh, P Singh, P Srivastava, D Kakkar, M Pathak… - Bioorganic …, 2023 - Elsevier
Abstract Serotonin (5-hydroxytryptamine) is a small molecule that acts both in the central
and peripheral nervous system as a neurotransmitter and a hormone, respectively …

Serotonin7 receptors (5-HT7Rs) and their ligands

M Leopoldo - Current medicinal chemistry, 2004 - ingentaconnect.com
Serotonin (5-HT) is involved in various physiological and pathological processes by
interaction with 14 distinct receptor subtypes, grouped in seven classes of receptors (5-HT 1 …

[HTML][HTML] The Serotonin 4 Receptor Subtype: A Target of Particular Interest, Especially for Brain Disorders

V Sgambato - International Journal of Molecular Sciences, 2024 - mdpi.com
In recent years, particular attention has been paid to the serotonin 4 receptor, which is well
expressed in the brain, but also peripherally in various organs. The cerebral distribution of …

Classification and signaling characteristics of 5-HT receptors

J Bockaert, S Claeysen, A Dumuis, P Marin - Handbook of Behavioral …, 2010 - Elsevier
Abstract Serotonin (5-hydroxytryptamine; 5-HT), along with its receptors, is one of the oldest
molecular devices assuming intercellular communication, being present as soon as simple …

Heterogeneity amongst 5-HT3 receptor subunits: is this significant?

N Yaakob, DT Malone, B Exintaris… - Current Molecular …, 2011 - ingentaconnect.com
The serotonin 3 (5-HT3) receptor is a ligand gated ion channel unlike the other 5-HT
receptors which are G protein coupled receptors. The functional 5-HT3 receptor forms a …