Persistent contralateral pain compromises exercise tolerance but does not alter corticomotor responses during repeated, submaximal isometric knee extensions to …

J Zhang, S Abel, M Macphail, SJ Aboodarda - Neuroscience, 2023 - Elsevier
Muscle pain is an important determinant of exercise tolerance, but its relationship with
neurophysiological responses during a submaximal exercise trial is unclear. The purpose of …

Effects of pre‐induced fatigue vs. concurrent pain on exercise tolerance, neuromuscular performance and corticospinal responses of locomotor muscles

SJ Aboodarda, D Iannetta, N Emami… - The Journal of …, 2020 - Wiley Online Library
Key points Fatigue and muscle pain induced in a remote muscle group has been shown to
alter neuromuscular performance in exercising muscles. Inhibitory neural feedback …

The effects of pain induced by blood flow occlusion in one leg on exercise tolerance and corticospinal excitability and inhibition of the contralateral leg in males

RA Azevedo, D Jazayeri, ST Yeung… - Applied physiology …, 2022 - cdnsciencepub.com
Experiencing pain in one leg can alter exercise tolerance and neuromuscular fatigue (NMF)
responses in the contralateral leg; however, the corticospinal modulations to nonlocal …

[HTML][HTML] The effect of hypertonic saline evoked muscle pain on neurophysiological changes and exercise performance in the contralateral limb

R Norbury, SA Smith, M Burnley, M Judge… - Experimental Brain …, 2022 - Springer
Non-local muscle pain may impair endurance performance through neurophysiological
mechanisms, but these are relatively unknown. This study examined the effects of muscle …

[HTML][HTML] Exercise-induced fatigue in one leg does not impair the neuromuscular performance in the contralateral leg but improves the excitability of the ipsilateral …

SJ Aboodarda, CXY Zhang, R Sharara, M Cline… - Brain sciences, 2019 - mdpi.com
To investigate the influence of pre-induced fatigue in one leg on neuromuscular
performance and corticospinal responses of the contralateral homologous muscles, three …

Spinal opioid receptor‐sensitive muscle afferents contribute to the fatigue‐induced increase in intracortical inhibition in healthy humans

L Hilty, K Lutz, K Maurer, T Rodenkirch… - Experimental …, 2011 - Wiley Online Library
We investigated the influence of spinal opioid receptor‐sensitive muscle afferents on cortical
changes following fatiguing unilateral knee‐extensor exercise. On separate days, seven …

[HTML][HTML] Experimental hand and knee pain cause differential effects on corticomotor excitability

DA Rice, GN Lewis, T Graven-Nielsen, R Luther… - The Journal of …, 2021 - Elsevier
Acute pain elicits a well-known inhibitory effect on upper limb corticomotor excitability,
whereas the temporal effects of lower-limb experimental pain and pain in a remote limb are …

[HTML][HTML] Reduced maximal force during acute anterior knee pain is associated with deficits in voluntary muscle activation

S Salomoni, K Tucker, F Hug, M McPhee, P Hodges - PLoS One, 2016 - journals.plos.org
Although maximal voluntary contraction (MVC) force is reduced during pain, studies using
interpolated twitch show no consistent reduction of voluntary muscle drive. The present …

Effect of movement‐evoked and tonic experimental pain on muscle force production

HV Cabral, V Devecchi, C Oxendale… - … Journal of Medicine …, 2024 - Wiley Online Library
Introduction When performing an exercise or a functional test, pain that is evoked by
movement or muscle contraction could be a stronger stimulus for changing how individuals …

Corticomotor excitability reduction induced by experimental pain remains unaffected by performing a working memory task as compared to staying at rest

DB Larsen, T Graven-Nielsen, RP Hirata… - Experimental Brain …, 2019 - Springer
Experimental pain inhibits primary motor cortex (M1) excitability. Attenuating pain-related
inhibition of M1 excitability may be useful during rehabilitation in individuals with pain. One …