Statins for the primary prevention of cardiovascular events in elderly patients: a picture from clinical practice without strong evidence from clinical trials

G Trifirò, M Alacqua, S Corrao, M Tari… - Journal of the American …, 2008 - iris.univr.it
Statins have been demonstrated to be beneficial for secondary prevention of cardiovascular
(CV) events also in the elderly. However, a great debate is ongoing about the actual …

Statins in primary prevention in people over 80 years

E Marcellaud, J Jost, A Tchalla, J Magne… - The American Journal of …, 2023 - Elsevier
In the much older population (≥ 80 years), the management of cardiovascular diseases
requires specific research to avoid a plain transposition of medical practice from younger …

Statins for the primary prevention of cardiovascular disease in the elderly

RN Lowe, JP Vande Griend… - The Consultant …, 2015 - ingentaconnect.com
Objective: The objective is to review the evidence evaluating the efficacy of statin therapy for
primary prevention of cardiovascular (CV) disease in the elderly. Data Sources: A literature …

Discontinuing statins or not in the elderly? Study protocol for a randomized controlled trial

F Bonnet, A Bénard, P Poulizac, M Afonso, A Maillard… - Trials, 2020 - Springer
Background The risk/benefit ratio of using statins for primary prevention of cardiovascular
(CV) events in elderly people has not been established. The main objectives of the present …

Statins for the primary prevention of cardiovascular events in older adults: a review of the evidence

R Ali, KP Alexander - The American Journal of Geriatric Pharmacotherapy, 2007 - Elsevier
BACKGROUND:: Although statins have been demonstrated to be beneficial for secondary
prevention in the elderly, their use for primary prevention has not been well described …

[HTML][HTML] Statins for primary cardiovascular prevention in the elderly

J Pedro-Botet, E Climent, JJ Chillarón… - Journal of geriatric …, 2015 - ncbi.nlm.nih.gov
The elderly population is increasing worldwide, with subjects> 65 years of age constituting
the fastest-growing age group. Furthermore, the elderly face the greatest risk and burden of …

Use of statin therapy to reduce cardiovascular risk in older patients

NK Wenger, SJ Lewis - Current gerontology and geriatrics …, 2010 - Wiley Online Library
Background. Cardiovascular disease is the principal cause of mortality in older individuals,
and more than 80% of deaths due to coronary heart disease or stroke occur in patients over …

Initiation of statin therapy: are there age limits?

DA Desai, S Zakaria, P Ouyang - Current atherosclerosis reports, 2012 - Springer
Cardiovascular disease (CVD) is the leading cause of death, with a higher prevalence in
older adults who form an increasing proportion of the population of the United States. Statin …

Statin prescribing in the elderly: special considerations

M Leya, NJ Stone - Current atherosclerosis reports, 2017 - Springer
Abstract Purpose of Review Our aim was to examine the current evidence behind
prescribing statins to individuals over 65 years of age with emphasis on those older than 75 …

Benefits and risks for primary prevention with statins in the elderly

JP Joseph, M Afonso, D Berdai, N Salles… - … (Paris, France: 1983), 2015 - europepmc.org
Method Methodic review of large randomized clinical trials and meta-analyzes that included
patients 75 years and older treated with statins in primary prevention. Results Since the …