AmpC β-lactamase-producing Enterobacterales: what a clinician should know

S Meini, C Tascini, M Cei, E Sozio, GM Rossolini - Infection, 2019 - Springer
Background Enterobacterales are among the most common causes of bacterial infections in
the community and among hospitalized patients, and multidrug-resistant (MDR) strains have …

Prevalence and molecular epidemiology of acquired AmpC β-lactamases and carbapenemases in Enterobacteriaceae isolates from 35 hospitals in Spain

E Miró, J Agüero, MN Larrosa, A Fernández… - European journal of …, 2013 - Springer
The purpose of this investigation was to determine the prevalence of plasmid-mediated
AmpC (pAmpC) and carbapenemases in Enterobacteriaceae collected from 35 hospitals in …

Practical approach for reliable detection of AmpC beta-lactamase-producing Enterobacteriaceae

S Polsfuss, GV Bloemberg, J Giger… - Journal of clinical …, 2011 - Am Soc Microbiol
In this prospective study all Enterobacteriaceae isolates (n= 2,129) recovered in the clinical
microbiology laboratory during October 2009 to April 2010 were analyzed for AmpC …

A primer on AmpC β-lactamases: necessary knowledge for an increasingly multidrug-resistant world

PD Tamma, Y Doi, RA Bonomo… - Clinical infectious …, 2019 - academic.oup.com
Understanding the nuances of AmpC β-lactamase–mediated resistance can be challenging,
even for the infectious diseases specialist. AmpC resistance can be classified into 3 …

Antibiotic therapy for inducible AmpC β-lactamase-producing Gram-negative bacilli: what are the alternatives to carbapenems, quinolones and aminoglycosides?

PNA Harris, JK Ferguson - International journal of antimicrobial agents, 2012 - Elsevier
Some bacteria that possess chromosomally determined AmpC β-lactamases may express
these enzymes at a high level following exposure to β-lactams, either by induction or …

Emergence of Antibiotic Resistance during Therapy for Infections Caused by Enterobacteriaceae Producing AmpC β-Lactamase: Implications for Antibiotic Use

SH Choi, JE Lee, SJ Park, SH Choi… - Antimicrobial agents …, 2008 - Am Soc Microbiol
ABSTRACT Enterobacter spp., Serratia marcescens, Citrobacter freundii, and Morganella
morganii are characterized by chromosomally encoded AmpC β-lactamases and possess …

AmpC β-lactamases

GA Jacoby - Clinical microbiology reviews, 2009 - Am Soc Microbiol
AmpC β-lactamases are clinically important cephalosporinases encoded on the
chromosomes of many of the Enterobacteriaceae and a few other organisms, where they …

Piperacillin-tazobactam versus other antibacterial agents for treatment of bloodstream infections due to AmpC β-lactamase-producing Enterobacteriaceae

L Cheng, BC Nelson, M Mehta, N Seval… - Antimicrobial agents …, 2017 - Am Soc Microbiol
In vivo induction of AmpC beta-lactamases produces high-level resistance to many beta-
lactam antibiotics in Enterobacteriaceae, often resulting in the need to use carbapenems or …

Infections caused by naturally AmpC-producing Enterobacteriaceae: Can we use third-generation cephalosporins? A narrative review

A Mizrahi, T Delerue, H Morel, A Le Monnier… - International journal of …, 2020 - Elsevier
The burden of antibiotic-resistant infections among Gram-negative bacteria is increasing.
Resistance to third-generation cephalosporins (3GCs) in Enterobacteriaceae is mainly …

Genotypic and Phenotypic Detection of AmpC β-lactamases in Enterobacter spp. Isolated from a Teaching Hospital in Malaysia

FI Mohd Khari, R Karunakaran, R Rosli, S Tee Tay - PloS one, 2016 - journals.plos.org
Objectives The objective of this study was to determine the occurrence of chromosomal and
plasmid-mediated β-lactamases (AmpC) genes in a collection of Malaysian isolates of …