The function of a neuron critically depends on the opening and closure of Ca2+ and K+
channels. Voltage-activated Ca2+ channels mediate transmembrane Ca2+ entry in …

G protein‐linked P2Y nucleotide receptors are known commonly to stimulate the
phosphoinositide signalling pathway. However, we have previously demonstrated that the …

Within the last 15 years, at least 8 different G protein-coupled P2Y receptors have been
characterized. These mediate slow metabotropic effects of nucleotides in neurons as well as …

The rat P2Y1 nucleotide receptor, the P2Y subtype abundant in the brain, was
heterologously expressed in rat superior cervical ganglion neurones by micro‐injection of …

Purine and pyrimidine nucleotides have been identified as potent extracellular signalling
molecules, acting at two classes of cell surface receptors, ionotropic P2X and metabotropic …

The diverse biological actions of extracellular nucleotides in tissues and cells are mediated
by two distinct classes of P2 receptor, P2X and P2Y. The G protein-coupled P2Y receptors …

Membrane-bound P2-receptors mediate the actions of extracellular nucleotides in cell-to-
cell signalling. P2X-receptors are ligand-gated ion channels, whereas P2Y-receptors belong …

The action of extracellular nucleotides, specifically the ability of adenine nucleotides to
induce coronary vasodilation and bradycardia, was first described more than 70 years ago …

The biological actions of extracellular nucleotides are exerted via two families of P2
receptors, P2X and P2Y. The metabotropic P2Y receptors comprise at least 7 distinct …

To search for inhibitory nucleotide receptors in the sympathoadrenal cell lineage of the rat,
voltage‐activated Ca2+ currents were recorded in PC12 cells after differentiation with nerve …